![](/images/graphics-bg.png)
Exploring Long Noncoding RNAs in Glioblastoma: Regulatory Mechanisms and Clinical Potentials
Joint Authors
Zeng, Tao
Li, Lei
Zhou, Yan
Gao, Liang
Source
International Journal of Genomics
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-12
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Gliomas are primary brain tumors presumably derived from glial cells.
The WHO grade IV glioblastoma (GBM), characterized by rapid cell proliferation, easily recrudescent, high morbidity, and mortality, is the most common, devastating, and lethal gliomas.
Molecular mechanisms underlying the pathogenesis and progression of GBMs with potential diagnostic and therapeutic value have been explored industriously.
With the advent of high-throughput technologies, numerous long noncoding RNAs (lncRNAs) aberrantly expressed in GBMs were discovered recently, some of them probably involved in GBM initiation, malignant progression, relapse and resistant to therapy, or showing diagnostic and prognostic value.
In this review, we summarized the profile of lncRNAs that has been extensively investigated in glioma research, with a focus on their regulatory mechanisms.
Then, their diagnostic, prognostic, and therapeutic implications were also discussed.
American Psychological Association (APA)
Zeng, Tao& Li, Lei& Zhou, Yan& Gao, Liang. 2018. Exploring Long Noncoding RNAs in Glioblastoma: Regulatory Mechanisms and Clinical Potentials. International Journal of Genomics،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1172701
Modern Language Association (MLA)
Zeng, Tao…[et al.]. Exploring Long Noncoding RNAs in Glioblastoma: Regulatory Mechanisms and Clinical Potentials. International Journal of Genomics No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1172701
American Medical Association (AMA)
Zeng, Tao& Li, Lei& Zhou, Yan& Gao, Liang. Exploring Long Noncoding RNAs in Glioblastoma: Regulatory Mechanisms and Clinical Potentials. International Journal of Genomics. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1172701
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1172701