Association between Sarcopenia and Renal Function in Patients with Diabetes: A Systematic Review and Meta-Analysis
Joint Authors
Ida, Satoshi
Kaneko, Ryutaro
Imataka, Kanako
Murata, Kazuya
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-18
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Previous studies involving patients with diabetes have indicated that sarcopenia is related to renal function.
The objective of the present study was to investigate the association between sarcopenia and urinary albumin level, urinary protein level, and estimated glomerular filtration rate (eGFR) in patients with diabetes.
A meta-analysis of observational studies was conducted.
A literature search was performed using MEDLINE, Cochrane Controlled Trials Registry, and ClinicalTrials.gov.
Data were extracted from studies investigating the association between sarcopenia and urinary albumin level, urinary protein level, and eGFR and by calculating odds ratio (OR) and 95% confidence intervals (CIs).
Statistical analysis was performed using a random-effects model to calculate pooled OR and 95% CI.
Six studies (2662 patients) that met the criteria were included in the meta-analysis.
Sarcopenia was significantly associated with urinary albumin level with a pooled OR of 2.11 (95% CI, 1.55–2.88; P<0.001).
The pooled ORs of the associations between sarcopenia and urinary protein level and decreased eGFR were 1.82 (95% CI, 1.13–2.92; P=0.01) and 3.75 (95% CI, 1.24–11.41), respectively.
Sarcopenia was significantly associated with urinary albumin level, urinary protein level, and decreased eGFR.
However, further investigations are needed, including meta-analyses with a larger number of studies.
American Psychological Association (APA)
Ida, Satoshi& Kaneko, Ryutaro& Imataka, Kanako& Murata, Kazuya. 2019. Association between Sarcopenia and Renal Function in Patients with Diabetes: A Systematic Review and Meta-Analysis. Journal of Diabetes Research،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1172702
Modern Language Association (MLA)
Ida, Satoshi…[et al.]. Association between Sarcopenia and Renal Function in Patients with Diabetes: A Systematic Review and Meta-Analysis. Journal of Diabetes Research No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1172702
American Medical Association (AMA)
Ida, Satoshi& Kaneko, Ryutaro& Imataka, Kanako& Murata, Kazuya. Association between Sarcopenia and Renal Function in Patients with Diabetes: A Systematic Review and Meta-Analysis. Journal of Diabetes Research. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1172702
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1172702