The Degree of Hyperglycemia Excursion in Patients of Kidney Transplantation (KT) or Liver Transplantation (LT) Assessed by Continuous Glucose Monitoring (CGM): Pilot Study
Joint Authors
Jin, Heung Yong
Lee, Kyung Ae
Kim, Yu Ji
Park, Tae Sun
Lee, Sik
Park, Sung Kwang
Hwang, Hong Pil
Yang, Jae Do
Ahn, Sung-Woo
Yu, Hee Chul
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-27
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Objective.
This study used a continuous glucose monitoring system (CGMS) to investigate the glucose profiles and assess the degree of hyperglycemic excursion after kidney or liver transplantation during the early period after operation.
Methods.
Patients to whom a CGMS was attached during a postoperative period of approximately one month after transplantation were included.
The CGM data of 31 patients including 24 with kidney transplantation (KT) and seven with liver transplantation (LT) were analyzed.
Results.
Hyperglycemia over 126 mg/dL (fasting) or 200 g/dL (postprandial) occurred in 42.1% (8/19) and 16.7% (1/6) of KT and LT patients, respectively, during this early period after transplantation, except for patients with preexisting diabetes (5 KT, 1 LT).
The average mean amplitude of glycemic excursion (MAGE) and mean absolute glucose (MAG) levels were 91.18±26.51 vs.
65.66±22.55 (P<0.05) and 24.62±7.78 vs.
18.18±7.07 (P<0.05) in KT vs.
LT patients, respectively, in patients without preexisting DM or PTDM patients who showed normal glucose levels.
Average increase from the lowest level to the peak glucose value was higher in KT patients than LT patients (P<0.05).
Conclusions.
The transplanted organ also needs to be considered as an important factor affecting glucose control and the occurrence of more severe glucose excursions in patients who receive transplantation although immunosuppression agents are well-known important factors; however, our study was limited to the early posttransplantation period.
Further studies involving CGM follow-up at regular intervals based on the time since transplantation are needed.
American Psychological Association (APA)
Jin, Heung Yong& Lee, Kyung Ae& Kim, Yu Ji& Park, Tae Sun& Lee, Sik& Park, Sung Kwang…[et al.]. 2019. The Degree of Hyperglycemia Excursion in Patients of Kidney Transplantation (KT) or Liver Transplantation (LT) Assessed by Continuous Glucose Monitoring (CGM): Pilot Study. Journal of Diabetes Research،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1172737
Modern Language Association (MLA)
Jin, Heung Yong…[et al.]. The Degree of Hyperglycemia Excursion in Patients of Kidney Transplantation (KT) or Liver Transplantation (LT) Assessed by Continuous Glucose Monitoring (CGM): Pilot Study. Journal of Diabetes Research No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1172737
American Medical Association (AMA)
Jin, Heung Yong& Lee, Kyung Ae& Kim, Yu Ji& Park, Tae Sun& Lee, Sik& Park, Sung Kwang…[et al.]. The Degree of Hyperglycemia Excursion in Patients of Kidney Transplantation (KT) or Liver Transplantation (LT) Assessed by Continuous Glucose Monitoring (CGM): Pilot Study. Journal of Diabetes Research. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1172737
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1172737