The Utility of Lower Glycemic Targets for Treating Gestational Diabetes: A Retrospective Study
Joint Authors
Hagen, Grace
Brown, Crystal
Dietrich, Jordan
Gibbs, Charles
Lee, Gene T.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-05
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
In vivo study of glucose homeostasis in pregnancy suggests normal glucose levels are lower than current glycemic targets used in gestational diabetes.
After the HAPO study results, our institution began using glycemic targets of fasting 85 mg/dL and 2-hour postprandial of 110 mg/dL.
We reviewed our results.
Methods.
A retrospective cohort of GDM patients that delivered at KUMC from January 2007 to May 2017 was reviewed.
All patients were diagnosed with the 2-step Carpenter-Coustan thresholds.
High targets were compared with low targets.
The primary outcome investigated was birthweight>90% (large for gestational age, LGA).
Results.
604 patients were studied, and 34% were treated with low glycemic targets.
Our unadjusted results showed that the low-target group had a lower incidence of LGA infants (24.0 vs.
31.8%), higher incidence of neonatal hypoglycemia (20.7 vs.
11.6%), and inductions (39.4 vs.
20.5%).
After adjustment for demographic variables, only a higher risk of inductions remained (aOR 2.54 (1.44, 4.49)).
Conclusion.
Lower glycemic targets did not produce large reductions in fetal overgrowth, but they were associated with a higher rate of inductions.
As there were no observed differences in maternal or neonatal outcomes otherwise, aiming for lower glycemic targets in GDM is likely not cost-effective.
American Psychological Association (APA)
Hagen, Grace& Brown, Crystal& Dietrich, Jordan& Gibbs, Charles& Lee, Gene T.. 2019. The Utility of Lower Glycemic Targets for Treating Gestational Diabetes: A Retrospective Study. Journal of Diabetes Research،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1173122
Modern Language Association (MLA)
Hagen, Grace…[et al.]. The Utility of Lower Glycemic Targets for Treating Gestational Diabetes: A Retrospective Study. Journal of Diabetes Research No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1173122
American Medical Association (AMA)
Hagen, Grace& Brown, Crystal& Dietrich, Jordan& Gibbs, Charles& Lee, Gene T.. The Utility of Lower Glycemic Targets for Treating Gestational Diabetes: A Retrospective Study. Journal of Diabetes Research. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1173122
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1173122