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Hypoglycemic Activity of Tilia americana, Borago officinalis, Chenopodium nuttalliae, and Piper sanctum on Wistar Rats
Joint Authors
Cordero-Pérez, Paula
Rivas Morales, Catalina
Leos-Rivas, Catalina
Oranday-Cárdenas, María A.
Rodríguez-Magaña, Martha P.
Moreno-Peña, Diana P.
García-Hernández, David G.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Diabetes mellitus (DM) is considered the epidemic of the 21st century.
Traditional medicine uses plants to treat DM; many of these have hypoglycemic effects in both animal models and diabetic patients.
Our objective was to evaluate the hypoglycemic activity of Tilia americana, Borago officinalis, Chenopodium nuttalliae, and Piper sanctum on diabetic rats.
The methanolic extracts of the plants under study were obtained by Soxhlet extraction.
Toxicity was evaluated on Artemia salina; the antioxidant potential was evaluated using the DPPH technique.
Hypoglycemic capacity at doses of 250 and 500 mg/kg was tested on Wistar rats with diabetes induced by alloxan (120 mg/kg).
The toxicity on A.
salina was null for the extracts of B.
officinalis and P.
sanctum, moderate for T.
americana, and highly toxic for C.
nuttalliae.
The relevant extract of T.
americana var.
mexicana showed antioxidant activity.
Three plants of the studied plants showed hypoglycemic activity: Tilia Americana (p=0.0142), Borago officinalis (p=0.0112), and Piper sanctum (p=0.0078); P.
sanctum was the one that showed the greatest reduction in glucose levels at a lower dose.
American Psychological Association (APA)
Rodríguez-Magaña, Martha P.& Cordero-Pérez, Paula& Rivas Morales, Catalina& Oranday-Cárdenas, María A.& Moreno-Peña, Diana P.& García-Hernández, David G.…[et al.]. 2019. Hypoglycemic Activity of Tilia americana, Borago officinalis, Chenopodium nuttalliae, and Piper sanctum on Wistar Rats. Journal of Diabetes Research،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1173234
Modern Language Association (MLA)
Rodríguez-Magaña, Martha P.…[et al.]. Hypoglycemic Activity of Tilia americana, Borago officinalis, Chenopodium nuttalliae, and Piper sanctum on Wistar Rats. Journal of Diabetes Research No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1173234
American Medical Association (AMA)
Rodríguez-Magaña, Martha P.& Cordero-Pérez, Paula& Rivas Morales, Catalina& Oranday-Cárdenas, María A.& Moreno-Peña, Diana P.& García-Hernández, David G.…[et al.]. Hypoglycemic Activity of Tilia americana, Borago officinalis, Chenopodium nuttalliae, and Piper sanctum on Wistar Rats. Journal of Diabetes Research. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1173234
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1173234