The Urinary Phosphate to Serum Fibroblast Growth Factor 23 Ratio, Deemed the Nephron Index, Is a Useful Clinical Index for Early Stage Chronic Kidney Disease in Patients with Type 2 Diabetes: An Observational Pilot Study
Joint Authors
Kuro-o, Makoto
Kakei, Masafumi
Yamada, Hodaka
Funazaki, Shunsuke
Ishikawa, San-e
Hara, Kazuo
Source
International Journal of Nephrology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-02
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Renal function decline is associated with progressive type 2 diabetes mellitus, which causes mineral and bone disorders.
In the present study, we defined the ratio of urinary phosphate excretion (mg/day) to serum fibroblast growth factor 23 as the nephron index.
We examined changes in the nephron index in type 2 diabetes patients with early stage chronic kidney disease (stages 1–3), enrolling 15 patients and retrospectively analysing the follow-up data.
After follow-up at 5.4 years, we observed no significant changes in the estimated glomerular filtration rate; the nephron index, however, was significantly reduced between the baseline and the follow-up.
We propose that the nephron index may be potentially useful as a biomarker for monitoring the decline of renal function in the early stages of diabetic chronic kidney disease patients.
American Psychological Association (APA)
Yamada, Hodaka& Kuro-o, Makoto& Funazaki, Shunsuke& Ishikawa, San-e& Kakei, Masafumi& Hara, Kazuo. 2018. The Urinary Phosphate to Serum Fibroblast Growth Factor 23 Ratio, Deemed the Nephron Index, Is a Useful Clinical Index for Early Stage Chronic Kidney Disease in Patients with Type 2 Diabetes: An Observational Pilot Study. International Journal of Nephrology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1173662
Modern Language Association (MLA)
Yamada, Hodaka…[et al.]. The Urinary Phosphate to Serum Fibroblast Growth Factor 23 Ratio, Deemed the Nephron Index, Is a Useful Clinical Index for Early Stage Chronic Kidney Disease in Patients with Type 2 Diabetes: An Observational Pilot Study. International Journal of Nephrology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1173662
American Medical Association (AMA)
Yamada, Hodaka& Kuro-o, Makoto& Funazaki, Shunsuke& Ishikawa, San-e& Kakei, Masafumi& Hara, Kazuo. The Urinary Phosphate to Serum Fibroblast Growth Factor 23 Ratio, Deemed the Nephron Index, Is a Useful Clinical Index for Early Stage Chronic Kidney Disease in Patients with Type 2 Diabetes: An Observational Pilot Study. International Journal of Nephrology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1173662
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1173662