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Irisin: A Potential Link between Physical Exercise and Metabolism—An Observational Study in Differently Trained Subjects, from Elite Athletes to Sedentary People
Joint Authors
Corsi Romanelli, Massimiliano M.
Benedini, Stefano
Luzi, Livio
Terruzzi, Ileana M.
Vianello, Elena
Banfi, Giuseppe
Invernizzi, Pietro Luigi
Dozio, Elena
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We compared irisin levels among groups of differently trained healthy individuals to explore the role of irisin as a physiological linker between exercise and metabolic health.
Irisin and biochemical parameters of glucose and lipid metabolism were assessed in 70 healthy volunteers stratified for sport performance level into four groups: (1) 20 elite athletes of national level, (2) 20 subelite athletes of local level, (3) 20 recreational athletes, and (4) 10 sedentary subjects.
All biochemical parameters were within the ranges of normality.
Fasting glucose, HOMA-IR, and total cholesterol levels were inversely related to the degree of physical activity.
HbA1c was higher in elite athletes compared to all the other groups (p<0.01).
A U-shaped relation between free fatty acids and the degree of physical activity was observed.
All groups showed similar plasma irisin levels.
After correction for the degree of insulin resistance (irisin/HOMA-IR), elite athletes showed higher levels compared to sedentary and recreational subjects (p<0.01 and p<0.05, resp.).
In addition, the number of metabolic parameters correlated with irisin increased at increasing the training status.
Our study suggests a correlation between sport performance, insulin sensitivity, and irisin levels.
Irisin may be one potential mediator of the beneficial effects of exercise on metabolic profile.
American Psychological Association (APA)
Benedini, Stefano& Dozio, Elena& Invernizzi, Pietro Luigi& Vianello, Elena& Banfi, Giuseppe& Terruzzi, Ileana M.…[et al.]. 2017. Irisin: A Potential Link between Physical Exercise and Metabolism—An Observational Study in Differently Trained Subjects, from Elite Athletes to Sedentary People. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1173726
Modern Language Association (MLA)
Benedini, Stefano…[et al.]. Irisin: A Potential Link between Physical Exercise and Metabolism—An Observational Study in Differently Trained Subjects, from Elite Athletes to Sedentary People. Journal of Diabetes Research No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1173726
American Medical Association (AMA)
Benedini, Stefano& Dozio, Elena& Invernizzi, Pietro Luigi& Vianello, Elena& Banfi, Giuseppe& Terruzzi, Ileana M.…[et al.]. Irisin: A Potential Link between Physical Exercise and Metabolism—An Observational Study in Differently Trained Subjects, from Elite Athletes to Sedentary People. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1173726
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1173726