A Comparison of Screening Tools for the Early Detection of Peripheral Neuropathy in Adults with and without Type 2 Diabetes
Joint Authors
Brown, Jennifer J.
Pribesh, Shana L.
Baskette, Kimberly G.
Colberg, Sheri R.
Vinik, Aaron I.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-08
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Objective.
Examine the effectiveness of the 128 Hz tuning fork, two monofilaments, and Norfolk Quality of Life Diabetic Neuropathy (QOL-DN) questionnaire as tools for the early detection of diabetic peripheral neuropathy (DPN) in overweight, obese, and inactive (OOI) adults or those who have prediabetes (PD) or type 2 diabetes (T2D).
Research Design and Methods.
Thirty-four adults (mean age 58.4 years ± 12.1) were divided by glycemia (10 OOI normoglycemic, 13 PD, and 11 T2D).
Sural nerves were tested bilaterally with the NC-stat DPNCheck to determine sural nerve amplitude potential (SNAP) and sural nerve conduction velocity (SNCV).
All other testing results were compared to SNAP and SNCV.
Results.
Total 1 g monofilament scores significantly correlated with SNAP values and yielded the highest sensitivity and specificity combinations of tested measures.
Total QOL-DN scores negatively correlated with SNAP values, as did QOL-DN symptoms.
QOL-DN activities of daily living correlated with the right SNAP, and the QOL-DN small fiber subscore correlated with SNCV.
Conclusions.
The 1 g monofilament and total QOL-DN are effective, low-cost tools for the early detection of DPN in OOI, PD, and T2D adults.
The 128 Hz tuning fork and 10 g monofilament may assist DPN screening as a tandem, but not primary, early DPN detection screening tools.
American Psychological Association (APA)
Brown, Jennifer J.& Pribesh, Shana L.& Baskette, Kimberly G.& Vinik, Aaron I.& Colberg, Sheri R.. 2017. A Comparison of Screening Tools for the Early Detection of Peripheral Neuropathy in Adults with and without Type 2 Diabetes. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1173807
Modern Language Association (MLA)
Brown, Jennifer J.…[et al.]. A Comparison of Screening Tools for the Early Detection of Peripheral Neuropathy in Adults with and without Type 2 Diabetes. Journal of Diabetes Research No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1173807
American Medical Association (AMA)
Brown, Jennifer J.& Pribesh, Shana L.& Baskette, Kimberly G.& Vinik, Aaron I.& Colberg, Sheri R.. A Comparison of Screening Tools for the Early Detection of Peripheral Neuropathy in Adults with and without Type 2 Diabetes. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1173807
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1173807