Investigating Factors Associated with Depressive Symptoms of Chronic Kidney Diseases in China with Type 2 Diabetes

Abstract EN

Aim.

To assess the depressive symptoms status of chronic kidney diseases in Nantong, China, with type 2 diabetes and to identify factors associated with depressive symptoms.

Methods.

In this cross-sectional analytic study, 210 type 2 diabetic patients were recruited from the Second Affiliated Hospital of Nantong University.

Depressive symptoms were assessed with the depression subscale of the Hospital Anxiety and Depression Scale (HAD-D).

The quality of life was measured with the RAND 36-Item Health Survey (SF-36).

And the independent risk factors of depressive symptoms were assessed by using a stepwise forward model of logistic regression analysis.

Results.

The mean age of the study subjects was 57.66 years (SD: 11.68).

Approximately 21.4% of subjects reported depressive symptoms (n=45).

Forward stepwise logistic regression analysis showed that female gender (P=0.010), hypertension (P=0.022), Stage IV (P=0.003), and Stage V (P<0.001) were significant risk factors for depressive symptoms.

The quality of life of individuals with HAD-D score <11 was significantly better compared with individuals with HAD-D score ≥ 11.

Conclusions.

These results indicate that clinicians should be aware that female patients with chronic kidney diseases with T2DM in their late stage with hypertension are at a marked increased risk of depressive symptoms.

Providing optimal care for the psychological health of this population is vital.