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Conjugated Linoleic Acid Grafting Improved Hemocompatibility of the Polycaprolactone Electrospun Membrane
Joint Authors
Phuong Thu, Ha
Hiep, Nguyen Thi
Tran, Nam Minh-Phuong
Nhi, Dang Ngọc Thao
Vo, Van Toi
Huynh, Toan Le-duc
Phan, Binh Ngoc
Phan, Thang Bach
Ha, Huong Thi-thanh
Truong, Long Phuoc
Huynh, Phu Dai
Tran, Ngoc Quyen
Source
International Journal of Polymer Science
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-16
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Polycaprolactone (PCL) is a versatile biomaterial with a wide range of medical applications, but its use in blood-contacting devices is hampered due to insufficient hemocompatibility.
In this work, electrospun polycaprolactone (PCL) membranes were chemically grafted with conjugated linoleic acid (CLA) to prevent induced blood coagulation.
The density of grafted CLA and its effects on the morphology and wettability of the membranes were examined.
The study also investigated how the membrane interacted with human whole blood and platelets to determine its antithrombotic properties.
As the results suggested, the grafting caused a negligible effect on the physical properties of the membrane but greatly improved its compatibility with blood, showing that the approach can be investigated further for blood-contacting applications.
American Psychological Association (APA)
Tran, Nam Minh-Phuong& Huynh, Toan Le-duc& Phan, Binh Ngoc& Nhi, Dang Ngọc Thao& Phan, Thang Bach& Ha, Huong Thi-thanh…[et al.]. 2020. Conjugated Linoleic Acid Grafting Improved Hemocompatibility of the Polycaprolactone Electrospun Membrane. International Journal of Polymer Science،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1173867
Modern Language Association (MLA)
Tran, Nam Minh-Phuong…[et al.]. Conjugated Linoleic Acid Grafting Improved Hemocompatibility of the Polycaprolactone Electrospun Membrane. International Journal of Polymer Science No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1173867
American Medical Association (AMA)
Tran, Nam Minh-Phuong& Huynh, Toan Le-duc& Phan, Binh Ngoc& Nhi, Dang Ngọc Thao& Phan, Thang Bach& Ha, Huong Thi-thanh…[et al.]. Conjugated Linoleic Acid Grafting Improved Hemocompatibility of the Polycaprolactone Electrospun Membrane. International Journal of Polymer Science. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1173867
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1173867