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Environmental and Life-Style Related Risk Factors for Sinonasal and Nasopharyngeal Malignancies among a Prospective Cohort in Jos, Nigeria
Joint Authors
Nimkur, Tonga L.
Kokong, Daniel D.
Ma’an, Nuhu D.
Adoga, Adeyi A.
Source
International Journal of Otolaryngology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Worldwide evidence indicates that environmental and life-style related factors are associated with increased risk for cancers in the head and neck region.
We aim to study the association between these risk factors and cancers in the sinonasal and nasopharyngeal regions in our environment.
Methods.
Longitudinal prospective cohort study at the Jos University Teaching Hospital, Jos, Nigeria.
Risk exposures were classified based on the International Agency for the Research on Cancer (IARC) classification of suspected carcinogens.
Associations between variables were analyzed using logistic regression.
Results.
We studied 44 patients with malignancies in nasopharynx (n= 24; 54.5%) and sinonasal regions (n= 20; 45.5%).
Male to female ratio is 1.9:1 and mean age is 45.2 years.
Alcohol was the commonest risk factor in males (n= 19; 43.2%) while cooking wood fumes were the commonest in females (n= 14; 31.8%) which was associated with increased risk for malignancies for all sites, showing ten times risk in nasal cancers (OR= 9.67; 95% CI 1.87- 9.88; p= 0.01).
Tobacco was associated with elevated risk of malignancies in the nasomaxillary and nasal regions.
Other risks were herbicides, pesticides, and chemical fertilizers in farmers.
Conclusion.
The significant risk exposures in females were cooking wood fumes and alcohol, tobacco, and exposure to agricultural chemicals in males.
Life-style modification and environmental changes to ensure clean air in Nigeria are essential to reduce risks.
American Psychological Association (APA)
Adoga, Adeyi A.& Kokong, Daniel D.& Nimkur, Tonga L.& Ma’an, Nuhu D.. 2018. Environmental and Life-Style Related Risk Factors for Sinonasal and Nasopharyngeal Malignancies among a Prospective Cohort in Jos, Nigeria. International Journal of Otolaryngology،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1173883
Modern Language Association (MLA)
Adoga, Adeyi A.…[et al.]. Environmental and Life-Style Related Risk Factors for Sinonasal and Nasopharyngeal Malignancies among a Prospective Cohort in Jos, Nigeria. International Journal of Otolaryngology No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1173883
American Medical Association (AMA)
Adoga, Adeyi A.& Kokong, Daniel D.& Nimkur, Tonga L.& Ma’an, Nuhu D.. Environmental and Life-Style Related Risk Factors for Sinonasal and Nasopharyngeal Malignancies among a Prospective Cohort in Jos, Nigeria. International Journal of Otolaryngology. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1173883
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1173883