Selective Screening Strategies for Gestational Diabetes: A Prospective Cohort Observational Study
Joint Authors
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-22
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Aim.
We aimed to develop a prediction model for the diagnosis of gestational diabetes and to evaluate the performance of published prediction tools on our population.
Methods.
We conducted a cohort study on nondiabetic women < 26 weeks gestation at a level 1 clinic in Johannesburg, South Africa.
At recruitment, participants completed a questionnaire and random basal glucose and HbA1c were evaluated.
A 75 g 2-hour OGTT was scheduled between 24–28 weeks gestation, as per FIGO guidelines.
A score was derived using multivariate logistic regression.
Published scoring systems were tested by deriving ROC curves.
Results.
In 554 women, RBG, BMI, and previous baby ≥ 4000 g were significant risk factors included for GDM, which were used to derive a nomogram-based score.
The logistic regression model for prediction of GDM had R2 0.143, Somer’s Dxy rank correlation 0.407, and Harrell’s c-score 0.703.
HbA1c did not improve predictive value of the nomogram at any threshold (e.g,.
at probability > 10%, 25.6% of cases were detected without the HbA1c, and 25.8% of cases would have been detected with the HbA1c).
The 9 published scoring systems performed poorly.
Conclusion.
We propose a nomogram-based score that can be used at first antenatal visit to identify women at high risk of GDM.
American Psychological Association (APA)
Adam, Sumaiya& Rheeder, Paul. 2017. Selective Screening Strategies for Gestational Diabetes: A Prospective Cohort Observational Study. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1173980
Modern Language Association (MLA)
Adam, Sumaiya& Rheeder, Paul. Selective Screening Strategies for Gestational Diabetes: A Prospective Cohort Observational Study. Journal of Diabetes Research No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1173980
American Medical Association (AMA)
Adam, Sumaiya& Rheeder, Paul. Selective Screening Strategies for Gestational Diabetes: A Prospective Cohort Observational Study. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1173980
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1173980