Correlation between C-reactive Protein with Malondialdehyde in Systemic Lupus Erythematosus Patients
Joint Authors
Atik, Nur
Putri Pratiwi, S.
Hamijoyo, Laniyati
Source
International Journal of Rheumatology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-01
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by an inflammatory process.
One of the inflammation markers that can be measured is C-reactive protein (CRP).
Another indicator of inflammation is malondialdehyde (MDA), though it is still uncommon to be analyzed in SLE patients.
The study looked for the MDA value and found a correlation with CRP.
A cross-sectional study design with a correlative analytical was performed.
CRP level data was taken from Hasan Sadikin lupus registry data, and MDA levels were analyzed from a bioarchive patient’s serum.
We collected the patients’ data who had CRP level from Hasan Sadikin lupus registry and analysed MDA levels from the serum sample.
MDA levels were analyzed using an ELISA method.
The data obtained were analyzed using the Pearson correlation and Eta correlation test.
The study involved 78 data patients as subjects.
It was found that the median of CRP and MDA was 0.85 mg/l and 153.10 ng/ml, respectively.
These results indicate that the CRP levels in SLE patients are still within normal limits.
Statistical analysis showed no correlation between CRP and MDA level (r=0.2, P>0.05).
Additionally, the correlation between CRP and MDA with organ involvement, such as lupus nephritis (LN), lupus cutaneous (LC), and lupus musculoskeletal (LM), showed no correlation (Fh There is no correlation between CRP and MDA levels in SLE patients, and specific organ involvement of the disease does not affect the correlation.
American Psychological Association (APA)
Atik, Nur& Putri Pratiwi, S.& Hamijoyo, Laniyati. 2020. Correlation between C-reactive Protein with Malondialdehyde in Systemic Lupus Erythematosus Patients. International Journal of Rheumatology،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1173985
Modern Language Association (MLA)
Atik, Nur…[et al.]. Correlation between C-reactive Protein with Malondialdehyde in Systemic Lupus Erythematosus Patients. International Journal of Rheumatology No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1173985
American Medical Association (AMA)
Atik, Nur& Putri Pratiwi, S.& Hamijoyo, Laniyati. Correlation between C-reactive Protein with Malondialdehyde in Systemic Lupus Erythematosus Patients. International Journal of Rheumatology. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1173985
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1173985