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Associated Factors with Biochemical Hypoglycemia during an Oral Glucose Tolerance Test in a Chinese Population
Joint Authors
Cai, Xiaoling
Ji, Linong
Han, Xueyao
Zhang, Simin
Zhou, Xianghai
Zhou, Lingli
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-22
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Aim.
To find the association between biochemical hypoglycemia on a 2-hour screening oral glucose tolerance test (OGTT) and insulin resistance.
Method.
Subjects of this study were sampled from the China National Diabetes and Metabolic Disorders Study that was conducted during 2007 and 2008.
Blood samples were drawn at 0, 30, and 120 minutes after the glucose load.
Biochemical hypoglycemia was defined as 2-hour glucose < 3.0 mmol/l.
Results.
In total, 26,606 participants were included, and 141 participants were diagnosed with biochemical hypoglycemia on a 2-hour OGTT.
Compared to participants with normal glucose tolerance (NGT), participants with biochemical hypoglycemia presented with a younger age, lower BMI, lower levels of fasting glucose, and lower levels of 30-minute and 2-hour OGTT glucose.
In terms of insulin resistance, participants with biochemical hypoglycemia showed higher levels of Matsuda ISI.
In terms of β-cell function, participants with biochemical hypoglycemia showed higher levels of Stumvoll early and late indexes.
A multivariate regression analysis indicated that higher levels of Matsuda ISI and higher levels of Stumvoll early and late indexes were associated with biochemical hypoglycemia independently.
Conclusion.
This study indicated that biochemical hypoglycemia might be associated with lower levels of insulin resistance but higher levels of β-cell function in a Chinese population.
American Psychological Association (APA)
Cai, Xiaoling& Han, Xueyao& Zhou, Xianghai& Zhou, Lingli& Zhang, Simin& Ji, Linong. 2017. Associated Factors with Biochemical Hypoglycemia during an Oral Glucose Tolerance Test in a Chinese Population. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1174148
Modern Language Association (MLA)
Cai, Xiaoling…[et al.]. Associated Factors with Biochemical Hypoglycemia during an Oral Glucose Tolerance Test in a Chinese Population. Journal of Diabetes Research No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1174148
American Medical Association (AMA)
Cai, Xiaoling& Han, Xueyao& Zhou, Xianghai& Zhou, Lingli& Zhang, Simin& Ji, Linong. Associated Factors with Biochemical Hypoglycemia during an Oral Glucose Tolerance Test in a Chinese Population. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1174148
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174148