The Management of Desmoid Tumors: A Retrospective Study of 30 Cases
Joint Authors
Zenzri, Yosr
Yahyaoui, Yosra
Charfi, Lamia
Ghodhbani, Zahra
Letaief, Feryel
Ayadi, Mouna
Mezlini, Amel
Source
International Journal of Surgical Oncology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-18
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objectives.
Desmoid tumor also called aggressive fibromatosis is a rare type of benign tumor.
It is a mesenchymal malignancy without metastatic potential.
The standard management is resection, but other options including observation may be discussed.
Desmoid-type fibromatosis may occur throughout the body, but the abdominal wall is the most common site.
The aim of our study was to assess the clinicoepidemiological profile, prognostic factors, and treatment outcome of desmoid tumors.
Methods.
A monocentric retrospective study was conducted over a period of 19 years between February 2000 and November 2019 at the oncology department of Salah Azaïz Institute.
Our study concerns 30 patients with desmoid tumor.
All data regarding patients were obtained from the medical record.
Results.
Thirty patients were included.
The median age was 35 years with a female predominance (sex ratio = 0.07).
A palpable mass was the most common complaint (n = 27).
Median tumor size was 5 cm.
The principal site of involvement was the abdominal wall (n = 14).
Surgery was performed in 27 patients.
The histopathology reports listed 14 (52%) cases with negative margins and 13 (48%) cases with positive margins.
Radiation therapy was performed in 2 patients.
One patient received tamoxifen.
Local recurrence occurred in 11 patients.
Two patients died of their desmoid tumor.
Abdominal wall tumors have less risk of recurrence compared with other sites (p=0.047).
Macroscopic margin involvement (R2) was the only prognostic factor influencing disease-free-survival (p=0.034).
Conclusion.
Desmoid tumors are aggressive tumors with a tendency for local recurrence.
Abdominal wall tumors have less risk of recurrence.
Macroscopic margin involvement was the only prognostic factor that affects disease-free-survival.
American Psychological Association (APA)
Zenzri, Yosr& Yahyaoui, Yosra& Charfi, Lamia& Ghodhbani, Zahra& Letaief, Feryel& Ayadi, Mouna…[et al.]. 2020. The Management of Desmoid Tumors: A Retrospective Study of 30 Cases. International Journal of Surgical Oncology،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1174176
Modern Language Association (MLA)
Zenzri, Yosr…[et al.]. The Management of Desmoid Tumors: A Retrospective Study of 30 Cases. International Journal of Surgical Oncology No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1174176
American Medical Association (AMA)
Zenzri, Yosr& Yahyaoui, Yosra& Charfi, Lamia& Ghodhbani, Zahra& Letaief, Feryel& Ayadi, Mouna…[et al.]. The Management of Desmoid Tumors: A Retrospective Study of 30 Cases. International Journal of Surgical Oncology. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1174176
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174176