Role of Nuclear Factor Erythroid 2-Related Factor 2 in Diabetic Nephropathy
Joint Authors
Cui, Wenpeng
Luo, Ping
Min, Xu
Xu, Xiaohong
Du, Bing
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-23
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Diabetic nephropathy (DN) is manifested as increased urinary protein level, decreased glomerular filtration rate, and final renal dysfunction.
DN is the leading cause of end-stage renal disease worldwide and causes a huge societal healthcare burden.
Since satisfied treatments are still limited, exploring new strategies for the treatment of this disease is urgently needed.
Oxidative stress takes part in the initiation and development of DN.
In addition, nuclear factor erythroid 2-related factor 2 (Nrf2) plays a key role in the cellular response to oxidative stress.
Thus, activation of Nrf2 seems to be a new choice for the treatment of DN.
In current review, we discussed and summarized the therapeutic effects of Nrf2 activation on DN from both basic and clinical studies.
American Psychological Association (APA)
Cui, Wenpeng& Min, Xu& Xu, Xiaohong& Du, Bing& Luo, Ping. 2017. Role of Nuclear Factor Erythroid 2-Related Factor 2 in Diabetic Nephropathy. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1174204
Modern Language Association (MLA)
Cui, Wenpeng…[et al.]. Role of Nuclear Factor Erythroid 2-Related Factor 2 in Diabetic Nephropathy. Journal of Diabetes Research No. 2017 (2017), pp.1-14.
https://search.emarefa.net/detail/BIM-1174204
American Medical Association (AMA)
Cui, Wenpeng& Min, Xu& Xu, Xiaohong& Du, Bing& Luo, Ping. Role of Nuclear Factor Erythroid 2-Related Factor 2 in Diabetic Nephropathy. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1174204
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174204
