High Prevalence of Autoimmune Diabetes and Poor Glycaemic Control among Adults in Madagascar: A Brief Report from a Humanitarian Health Campaign in Ambanja
Joint Authors
Angeletti, Silvia
Napoli, Nicola
Maddaloni, Ernesto
Pozzilli, Paolo
Tiberti, Claudio
Pastore, Giovanlorenzo
Del Buono, Marco Giuseppe
Porcari, Aldostefano
Fittipaldi, Mario
Garilli, Francesco
Mottini, Giovanni
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-06
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Madagascar is a geographically isolated country considered a biodiversity hotspot with unique genomics.
Both the low-income and the geographical isolation represent risk factors for the development of diabetes.
During a humanitarian health campaign conducted in Ambanja, a rural city in the northern part of Madagascar, we identified 42 adult subjects with diabetes and compared their features to 24 randomly enrolled healthy controls.
42.9% (n=18) of diabetic subjects showed HbA1c values ≥ 9.0%.
Unexpectedly, waist circumference and BMI were similar in people with diabetes and controls.
Different from the healthy controls, diabetic subjects showed a low prevalence of obesity (5.7% versus 30%, p=0.02).
Accordingly, we found a high prevalence of autoimmune diabetes as 12% of people with diabetes showed positivity for the autoantibody against glutamic acid decarboxylase.
Diabetic subjects with positive autoantibody had higher HbA1c values (11.3 ± 4.1% versus 8.3 ± 2.6%, p=0.03) compared to diabetic subjects with negative autoantibody.
In conclusion, here we describe the presence of diabetes and its features in a rural area of Northern Madagascar, documenting poor glycaemic control and a high prevalence of autoimmune diabetes.
These data highlight that the diabetes epidemic involves every corner of the world possibly with different patterns and features.
American Psychological Association (APA)
Maddaloni, Ernesto& Pastore, Giovanlorenzo& Del Buono, Marco Giuseppe& Porcari, Aldostefano& Fittipaldi, Mario& Garilli, Francesco…[et al.]. 2017. High Prevalence of Autoimmune Diabetes and Poor Glycaemic Control among Adults in Madagascar: A Brief Report from a Humanitarian Health Campaign in Ambanja. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1174216
Modern Language Association (MLA)
Maddaloni, Ernesto…[et al.]. High Prevalence of Autoimmune Diabetes and Poor Glycaemic Control among Adults in Madagascar: A Brief Report from a Humanitarian Health Campaign in Ambanja. Journal of Diabetes Research No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1174216
American Medical Association (AMA)
Maddaloni, Ernesto& Pastore, Giovanlorenzo& Del Buono, Marco Giuseppe& Porcari, Aldostefano& Fittipaldi, Mario& Garilli, Francesco…[et al.]. High Prevalence of Autoimmune Diabetes and Poor Glycaemic Control among Adults in Madagascar: A Brief Report from a Humanitarian Health Campaign in Ambanja. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1174216
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174216