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The Comparison of Nailfold Capillaroscopy between Juvenile Systemic Lupus Erythematosus and Healthy Controls: Correlation with Laboratory and Clinical Parameters
Joint Authors
Ziaee, Vahid
Assari, Raheleh
Raeeskarami, Sayed-Reza
Namazi, Navid
Najafizadeh, Seyed-Reza
Hassannejad, Zohreh
Source
International Journal of Vascular Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-27
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Nailfold capillaroscopy is a noninvasive technique to recognize peripheral microangiopathy, which is an important feature in systemic lupus erythematosus (SLE).
The aims of the present study were to investigate the prevalence of nailfold capillaroscopy (NFC) changes in juvenile systemic lupus erythematosus (JSLE), find out patterns of these changes, and correlate findings with clinical and laboratory parameters.
Methods.
Forty-nine patients with SLE, all meeting the 1997 revised ACR criteria for SLE classification, and 30 healthy controls were included.
A digital video camera was used to capture nailfold capillary images.
Computerized image processing was used for analysis.
Results.
Different abnormal NFC changes were observed with abnormal morphology, the increased diameter and abnormal loop densities in 55.1%, 93.9%, and 26.5% of the patients, respectively.
No statistically significant differences were depicted between capillaroscopy with age, gender, autoantibodies (APLs, anti-ds DNA), antiphospholipid antibody syndrome, thrombotic angiopathy, renal function tests (Bun, Cr), and abnormal urine analysis.
However, a significant correlation was found between the branched pattern and the CNS involvement group (P value <0.03).
Conclusions.
Different abnormal NFC changes are quite common among patients with SLE, and nailfold capillaroscopy is an effective method to monitor such changes.
Treatment strategies may change in the branched pattern of nailfold capillaroscopy due to CNS involvement.
American Psychological Association (APA)
Raeeskarami, Sayed-Reza& Namazi, Navid& Assari, Raheleh& Najafizadeh, Seyed-Reza& Hassannejad, Zohreh& Ziaee, Vahid. 2020. The Comparison of Nailfold Capillaroscopy between Juvenile Systemic Lupus Erythematosus and Healthy Controls: Correlation with Laboratory and Clinical Parameters. International Journal of Vascular Medicine،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1174230
Modern Language Association (MLA)
Raeeskarami, Sayed-Reza…[et al.]. The Comparison of Nailfold Capillaroscopy between Juvenile Systemic Lupus Erythematosus and Healthy Controls: Correlation with Laboratory and Clinical Parameters. International Journal of Vascular Medicine No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1174230
American Medical Association (AMA)
Raeeskarami, Sayed-Reza& Namazi, Navid& Assari, Raheleh& Najafizadeh, Seyed-Reza& Hassannejad, Zohreh& Ziaee, Vahid. The Comparison of Nailfold Capillaroscopy between Juvenile Systemic Lupus Erythematosus and Healthy Controls: Correlation with Laboratory and Clinical Parameters. International Journal of Vascular Medicine. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1174230
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174230