Clinical Phenotype of Diabetic Peripheral Neuropathy and Relation to Symptom Patterns: Cluster and Factor Analysis in Patients with Type 2 Diabetes in Korea
Joint Authors
Cha, Bong-Yun
Park, Tae Sun
Won, Jong Chul
Im, Yong-Jin
Lee, Ji-Hyun
Kim, Chong Hwa
Kwon, Hyuk-Sang
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-13
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objectives.
Patients with diabetic peripheral neuropathy (DPN) is the most common complication.
However, patients are usually suffering from not only diverse sensory deficit but also neuropathy-related discomforts.
The aim of this study is to identify distinct groups of patients with DPN with respect to its clinical impacts on symptom patterns and comorbidities.
Methods.
A hierarchical cluster analysis and factor analysis were performed to identify relevant subgroups of patients with DPN (n=1338) and symptom patterns.
Results.
Patients with DPN were divided into three clusters: asymptomatic (cluster 1, n=448, 33.5%), moderate symptoms with disturbed sleep (cluster 2, n=562, 42.0%), and severe symptoms with decreased quality of life (cluster 3, n=328, 24.5%).
Patients in cluster 3, compared with clusters 1 and 2, were characterized by higher levels of HbA1c and more severe pain and physical impairments.
Patients in cluster 2 had moderate pain levels but disturbed sleep patterns comparable to those in cluster 3.
The frequency of symptoms on each item of MNSI by “painful” symptom pattern showed a similar distribution pattern with increasing intensities along the three clusters.
Conclusions.
Cluster and factor analysis endorsed the use of comprehensive and symptomatic subgrouping to individualize the evaluation of patients with DPN.
American Psychological Association (APA)
Won, Jong Chul& Im, Yong-Jin& Lee, Ji-Hyun& Kim, Chong Hwa& Kwon, Hyuk-Sang& Cha, Bong-Yun…[et al.]. 2017. Clinical Phenotype of Diabetic Peripheral Neuropathy and Relation to Symptom Patterns: Cluster and Factor Analysis in Patients with Type 2 Diabetes in Korea. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1174477
Modern Language Association (MLA)
Won, Jong Chul…[et al.]. Clinical Phenotype of Diabetic Peripheral Neuropathy and Relation to Symptom Patterns: Cluster and Factor Analysis in Patients with Type 2 Diabetes in Korea. Journal of Diabetes Research No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1174477
American Medical Association (AMA)
Won, Jong Chul& Im, Yong-Jin& Lee, Ji-Hyun& Kim, Chong Hwa& Kwon, Hyuk-Sang& Cha, Bong-Yun…[et al.]. Clinical Phenotype of Diabetic Peripheral Neuropathy and Relation to Symptom Patterns: Cluster and Factor Analysis in Patients with Type 2 Diabetes in Korea. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1174477
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174477