Evaluation of the Use of Different Solvents for Phytochemical Constituents, Antioxidants, and In Vitro Anti-Inflammatory Activities of Severinia buxifolia
Joint Authors
Nguyen, Hoang-Chinh
Truong, Dieu-Hien
Nguyen, Dinh Hieu
Ta, Nhat Thuy Anh
Bui, Anh Vo
Do, Tuong Ha
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-03
Country of Publication
Egypt
No. of Pages
9
Abstract EN
Severinia buxifolia (Rutaceae) is a promising source of bioactive compounds since it has been traditionally used for the treatment of various diseases.
The present study aimed at evaluating the impact of different solvents on extraction yields, phytochemical constituents and antioxidants, and in vitro anti-inflammatory activities of S.
buxifolia.
The results showed that the used solvents took an important role in the yield of extraction, the content of chemical components, and the tested biological activities.
Methanol was identified as the most effective solvent for the extraction, resulting in the highest extraction yield (33.2%) as well as the highest content of phenolic (13.36 mg GAE/g DW), flavonoid (1.92 mg QE/g DW), alkaloid (1.40 mg AE/g DW), and terpenoids (1.25%, w/w).
The extract obtained from methanol exhibited high capacity of antioxidant (IC50 value of 16.99 μg/mL) and in vitro anti-inflammatory activity (i.e., albumin denaturation: IC50 = 28.86 μg/mL; antiproteinase activity: IC50 = 414.29 μg/mL; and membrane stabilization: IC50 = 319 μg/mL).
The antioxidant activity of the S.
buxifolia extract was found to be 3-fold higher than ascorbic acid, and the anti-inflammatory activity of S.
buxifolia extract was comparable to aspirin.
Therefore, methanol is recommended as the optimal solvent to obtain high content of phytochemical constituents as well as high antioxidants and in vitro anti-inflammatory constituents from the branches of S.
buxifolia for utilization in pharmacognosy.
American Psychological Association (APA)
Truong, Dieu-Hien& Nguyen, Dinh Hieu& Ta, Nhat Thuy Anh& Bui, Anh Vo& Do, Tuong Ha& Nguyen, Hoang-Chinh. 2019. Evaluation of the Use of Different Solvents for Phytochemical Constituents, Antioxidants, and In Vitro Anti-Inflammatory Activities of Severinia buxifolia. Journal of Food Quality،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1174527
Modern Language Association (MLA)
Truong, Dieu-Hien…[et al.]. Evaluation of the Use of Different Solvents for Phytochemical Constituents, Antioxidants, and In Vitro Anti-Inflammatory Activities of Severinia buxifolia. Journal of Food Quality No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1174527
American Medical Association (AMA)
Truong, Dieu-Hien& Nguyen, Dinh Hieu& Ta, Nhat Thuy Anh& Bui, Anh Vo& Do, Tuong Ha& Nguyen, Hoang-Chinh. Evaluation of the Use of Different Solvents for Phytochemical Constituents, Antioxidants, and In Vitro Anti-Inflammatory Activities of Severinia buxifolia. Journal of Food Quality. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1174527
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174527