TNF-Alpha in Peripheral Neuropathy Patients with Impaired Glucose Regulation
Joint Authors
Li, Xia
Zhu, Ju
Liu, Na
Liu, Jie
Zhang, Zhecheng
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Impaired glucose regulation (IGR) is the prestate of diabetes; about 1/3 of IGR patients will develop to diabetes finally.
In this study, we investigated the serum tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) levels in peripheral neuropathy impaired patients with impaired glucose regulation (IGR).
A total of 70 IGR patients received the conventional nerve conduction test, including 30 patients with peripheral neuropathy (PN) and 40 patients without peripheral neuropathy (NPN).
The other 40 healthy individuals were recruited as controls.
The serum TNF-α and IL-6 in IGR patients were higher than in control group, and serum TNF-α and IL-6 levels in IGR-PN group were higher than in IGR-NPN group (27.7±17.8 versus 13.1±6.7 pg/mL and 18.1±17.7 versus 6.4±3.7 pg/mL, resp., both p<0.05).
Multifactors logistic regression analysis showed that TNF-α (OR = 0.893; p=0.009) was an independent factor affecting whether IGR could combine with peripheral neuropathy.
TNF-α and IL-6 could aggregate peripheral neuropathy in impaired glucose regulation patients; TNF-α might be independent risk factor for peripheral neuropathy in glucose regulation impaired patients.
American Psychological Association (APA)
Li, Xia& Zhu, Ju& Liu, Na& Liu, Jie& Zhang, Zhecheng. 2017. TNF-Alpha in Peripheral Neuropathy Patients with Impaired Glucose Regulation. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1174649
Modern Language Association (MLA)
Li, Xia…[et al.]. TNF-Alpha in Peripheral Neuropathy Patients with Impaired Glucose Regulation. Journal of Diabetes Research No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1174649
American Medical Association (AMA)
Li, Xia& Zhu, Ju& Liu, Na& Liu, Jie& Zhang, Zhecheng. TNF-Alpha in Peripheral Neuropathy Patients with Impaired Glucose Regulation. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1174649
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174649