The Relationship between Cardiovascular Autonomic Dysfunction and Ocular Abnormality in Chinese T2DM
Joint Authors
Wang, Dandan
Shen, Baiyu
Wu, Chunrong
Xue, Yanyan
Liu, Yanjun
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-01
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
This study aims to explore the relationship between autonomic nerve dysfunction—assessed by cardiovascular autonomic neuropathy risk score (CAN-RS)—and ocular abnormality in Chinese type 2 diabetes mellitus (T2DM).
Method.
This is a cross-sectional study.
A total of 335 subjects with T2DM were enrolled.
The state of visual acuity, the lens, the vitreous, and the fundus were tested by professional ophthalmic instruments.
The electrochemical skin conductance (ESC) of the hands and feet was measured by SUDOSCAN, from which a cardiovascular autonomic neuropathy risk score (CAN-RS) was calculated.
Receiver operating characteristic (ROC) curves were drawn to evaluate the feasibility and accuracy of CAN-RS in diabetic oculopathy screening.
Results.
Abnormalities of the lens, vitreous, and fundus accounted for 7.8%, 5.1%, and 9.9%, respectively, in this study.
The means of hands and feet ESC were higher than 60 μS, and CAN-RS was 33.1 ± 14.8%.
In logistic regression analysis, CAN-RS was positively associated with lens (OR = 1.055, P<0.001) and vitreous (OR = 1.044, P<0.01) abnormality.
The area under ROC to detect lens and vitreous abnormality was 0.713 and 0.725, respectively.
Conclusion.
CAN-RS, a cardiac autonomic nerve dysfunction index calculated by SUDOSCAN, may be a promising index for lens and vitreous abnormality screening in T2DM patients.
Further studies are needed to confirm the conclusion.
American Psychological Association (APA)
Wang, Dandan& Shen, Baiyu& Wu, Chunrong& Xue, Yanyan& Liu, Yanjun. 2017. The Relationship between Cardiovascular Autonomic Dysfunction and Ocular Abnormality in Chinese T2DM. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1174672
Modern Language Association (MLA)
Wang, Dandan…[et al.]. The Relationship between Cardiovascular Autonomic Dysfunction and Ocular Abnormality in Chinese T2DM. Journal of Diabetes Research No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1174672
American Medical Association (AMA)
Wang, Dandan& Shen, Baiyu& Wu, Chunrong& Xue, Yanyan& Liu, Yanjun. The Relationship between Cardiovascular Autonomic Dysfunction and Ocular Abnormality in Chinese T2DM. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1174672
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174672