Chemical Comparison of White Ginseng before and after Extrusion by UHPLC-Q-Orbitrap-MSMS and Multivariate Statistical Analysis

Joint Authors

Guo, Yun-Long
Zhao, Yi-Lin
Xu, Xiu-Ying
Zhao, Cheng-Bin
Zheng, Ming-Zhu
Liu, Shu-Ying
Wu, Yu-Zhu
Liu, Jing-Sheng
Wang, Yang
Zhang, Hao

Source

Journal of Analytical Methods in Chemistry

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-10-07

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Chemistry

Abstract EN

Ultrahigh-performance liquid chromatography Quadrupole-Orbitrap tandem mass spectrometry (UHPLC-Q-Orbitrap-MS/MS) was used to compare the composition of ginsenosides in white ginseng (WG) and extruded white ginseng (EWG).

A total of 45 saponins, including original neutral ginsenosides, malonyl-ginsenosides, and chemical transformation of ginsenosides, were successfully identified in both WG and EWG.

Multivariate statistical analyses including supervised orthogonal partial least squared discrimination analysis (OPLS-DA) and hierarchical clustering analysis (HCA) were used to analyze components of white ginseng before and after extrusion.

As a result, three ginsenosides (malonyl (M)-Rb1, M-Rb2, and M-Rc) were found to be increased in WG, while three ginsenosides (Rb2, Rc, and Rg1) were elevated in EWG.

In the OPLS-DA S-plot, the different compositions of ginsenoside that were distinguished between WG and EWG were screened out.

Experimental results indicate that the UHPLC-Q-Orbitrap-MS/MS is a useful tool to characterize variations of ginsenosides in WG and EWG.

American Psychological Association (APA)

Guo, Yun-Long& Wang, Yang& Zhao, Yi-Lin& Xu, Xiu-Ying& Zhang, Hao& Zhao, Cheng-Bin…[et al.]. 2020. Chemical Comparison of White Ginseng before and after Extrusion by UHPLC-Q-Orbitrap-MSMS and Multivariate Statistical Analysis. Journal of Analytical Methods in Chemistry،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1174752

Modern Language Association (MLA)

Guo, Yun-Long…[et al.]. Chemical Comparison of White Ginseng before and after Extrusion by UHPLC-Q-Orbitrap-MSMS and Multivariate Statistical Analysis. Journal of Analytical Methods in Chemistry No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1174752

American Medical Association (AMA)

Guo, Yun-Long& Wang, Yang& Zhao, Yi-Lin& Xu, Xiu-Ying& Zhang, Hao& Zhao, Cheng-Bin…[et al.]. Chemical Comparison of White Ginseng before and after Extrusion by UHPLC-Q-Orbitrap-MSMS and Multivariate Statistical Analysis. Journal of Analytical Methods in Chemistry. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1174752

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1174752