Circulating Nesfatin-1 Levels and Type 2 Diabetes: A Systematic Review and Meta-Analysis
Joint Authors
Dong, Jing
Zhai, Ting
Li, Shi-Zhen
Fan, Xin-Tong
Tian, Zhao
Lu, Xiao-Qing
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The role of nesfatin-1 in glucose homeostasis has been investigated previously.
However, although numerous studies have examined the relationships between circulating nesfatin-1 levels and type 2 diabetes, the conclusions are contradictory.
We aimed to probe the relationship between circulating nesfatin-1 levels and type 2 diabetes by meta-analysis.
Seven studies including 328 type 2 diabetes patients and 294 control subjects were included.
Although there was no obvious difference in circulating nesfatin-1 levels between patients with type 2 diabetes and the control group (MD = −0.04; 95% CI = −0.32 to −0.23), subgroup analysis showed higher nesfatin-1 levels in newly diagnosed type 2 diabetes patients (MD = 0.59; 95% CI = 0.45 to 0.74) and significantly lower nesfatin-1 levels in type 2 diabetes patients receiving antidiabetic treatment (MD = −0.26; 95% CI = −0.33 to −0.20).
In conclusion, the analysis supports a relationship between circulating nesfatin-1 levels and type 2 diabetes, where newly diagnosed type 2 diabetes was associated with an elevated Nesfatin-1 level, and type 2 diabetes patients receiving antidiabetic treatment showed lower circulating nesfatin-1 levels.
American Psychological Association (APA)
Zhai, Ting& Li, Shi-Zhen& Fan, Xin-Tong& Tian, Zhao& Lu, Xiao-Qing& Dong, Jing. 2017. Circulating Nesfatin-1 Levels and Type 2 Diabetes: A Systematic Review and Meta-Analysis. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1174769
Modern Language Association (MLA)
Zhai, Ting…[et al.]. Circulating Nesfatin-1 Levels and Type 2 Diabetes: A Systematic Review and Meta-Analysis. Journal of Diabetes Research No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1174769
American Medical Association (AMA)
Zhai, Ting& Li, Shi-Zhen& Fan, Xin-Tong& Tian, Zhao& Lu, Xiao-Qing& Dong, Jing. Circulating Nesfatin-1 Levels and Type 2 Diabetes: A Systematic Review and Meta-Analysis. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1174769
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174769