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Epigenetic Regulations in Diabetic Nephropathy
Joint Authors
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-19
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Diabetic nephropathy (DN) is a chronic complication of diabetes and the most common cause of end-stage kidney disease.
It has been reported that multiple factors are involved in the pathogenesis of DN, while the molecular mechanisms that lead to DN are still not fully understood.
Numerous risk factors for the development of diabetic nephropathy have been proposed, including ethnicity and inherited genetic differences.
Recently, with the development of high-throughput technologies, there is emerging evidence that suggests the important role of epigenetic mechanisms in the pathogenesis of DN.
Epigenetic regulations, including DNA methylation, noncoding RNAs, and histone modifications, play a pivotal role in DN pathogenesis by a second layer of gene regulation.
All these findings can contribute to developing novel therapies for DN.
American Psychological Association (APA)
Lu, Zeyuan& Liu, Na& Wang, Feng. 2017. Epigenetic Regulations in Diabetic Nephropathy. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1174772
Modern Language Association (MLA)
Lu, Zeyuan…[et al.]. Epigenetic Regulations in Diabetic Nephropathy. Journal of Diabetes Research No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1174772
American Medical Association (AMA)
Lu, Zeyuan& Liu, Na& Wang, Feng. Epigenetic Regulations in Diabetic Nephropathy. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1174772
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174772