![](/images/graphics-bg.png)
Vitamin D Supplementation Improves Mood in Women with Type 2 Diabetes
Joint Authors
Byrn, Mary A.
Adams, William
Penckofer, Sue
Emanuele, Mary Ann
Mumby, Patricia
Kouba, Joanne
Wallis, Diane E.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-07
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Objective.
The aim of this study was to determine the effect of vitamin D supplementation on improving mood (depression and anxiety) and health status (mental and physical) in women with type 2 diabetes mellitus (T2DM).
Methods.
Fifty women with T2DM and significant depressive symptomology were enrolled into the “Sunshine Study,” where weekly vitamin D supplementation (ergocalciferol, 50,000 IU) was given to all participants for six months.
The main outcomes included (1) depression (Center for Epidemiologic Studies Depression, CES-D, and Patient Health Questionnaire, PHQ-9), (2) anxiety (State-Trait Anxiety), and (3) health status (Short Form, SF-12).
Results.
Forty-six women (92%) completed all visits.
There was a significant decrease in depression (CES-D and PHQ-9, p<0.001) and anxiety (state and trait, p<0.001).
An improvement in mental health status (SF-12, p<0.001) was also found.
After controlling for covariates (race, season of enrollment, baseline vitamin D, baseline depression (PHQ-9), and body mass index), the decline in depression remained significant (CES-D, p<0.001).
There was a trend for a better response to supplementation for women who were not taking medications for mood (antidepressants or anxiolytics) (p=0.07).
Conclusions.
Randomized trials to confirm that vitamin D supplementation can improve mood and health status in T2DM women are needed.
American Psychological Association (APA)
Penckofer, Sue& Byrn, Mary A.& Adams, William& Emanuele, Mary Ann& Mumby, Patricia& Kouba, Joanne…[et al.]. 2017. Vitamin D Supplementation Improves Mood in Women with Type 2 Diabetes. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1174827
Modern Language Association (MLA)
Penckofer, Sue…[et al.]. Vitamin D Supplementation Improves Mood in Women with Type 2 Diabetes. Journal of Diabetes Research No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1174827
American Medical Association (AMA)
Penckofer, Sue& Byrn, Mary A.& Adams, William& Emanuele, Mary Ann& Mumby, Patricia& Kouba, Joanne…[et al.]. Vitamin D Supplementation Improves Mood in Women with Type 2 Diabetes. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1174827
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174827