Internal Standards for Quantitative Analysis of Chemical Warfare Agents by the GCMS Method: Nerve Agents
Joint Authors
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-11
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
General conditions and requirements for an internal standard useful in the determination of chemical warfare agents (CWAs) by the method of gas chromatography coupled with mass detection (GC/MS) were defined.
The determination is based on a GC/MS analysis of a mixture of a CWA with an internal standard, conversion of the TIC chromatogram to a chromatogram extracted at a particular m/z ratio, and calculation of the CWA concentration from the internal standard concentration, response factor, and chromatographic peak areas.
Available internal standards were identified, and they were verified for seven organophosphorus nerve-paralysing agents.
Corresponding response factors were determined as a ratio of gradients of the linear functions of the peak area and compound concentration.
Linearity, repeatability, and accuracy of the measurements were evaluated.
The determination can be performed on all GC/MS systems of the Fire Rescue Service of the Czech Republic (FRS), where no CWA standards are available.
American Psychological Association (APA)
Capoun, Tomas& Krykorkova, Jana. 2020. Internal Standards for Quantitative Analysis of Chemical Warfare Agents by the GCMS Method: Nerve Agents. Journal of Analytical Methods in Chemistry،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1174965
Modern Language Association (MLA)
Capoun, Tomas& Krykorkova, Jana. Internal Standards for Quantitative Analysis of Chemical Warfare Agents by the GCMS Method: Nerve Agents. Journal of Analytical Methods in Chemistry No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1174965
American Medical Association (AMA)
Capoun, Tomas& Krykorkova, Jana. Internal Standards for Quantitative Analysis of Chemical Warfare Agents by the GCMS Method: Nerve Agents. Journal of Analytical Methods in Chemistry. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1174965
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1174965