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Preparation of Keratin-Glycine Metal Complexes and Their Scavenging Activity for Superoxide Anion Radicals
Joint Authors
Wang, Jianfeng
Li, Xiaoxiao
He, Yufeng
Song, Pengfei
Wang, Rongmin
Source
International Journal of Polymer Science
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
To address the problem of limited application of natural SOD, the development of SOD mimic enzymes is of great importance for bioantioxidation.
Herein, we report on a new type of biopolymer antioxidant with excellent scavenging activity for O2•-, keratin-glycine metal complexes (FK-GlyM, M = Zn, Cu, Mn, Ni).
They are prepared by feather keratin firstly combined with glycine and then metal ions.
Using FT-IR, TG, CD, and SEM, the performance of the obtained complexes (FK-GlyM) for scavenging O2•- is analysed and investigated.
Importantly, the scavenging activity of FK-GlyCu is excellent in all FK-GlyM, and FK-GlyCu60 has the most excellent anti-O2•- activity in all FK-GlyCux, of which EC50 and degree of simulation were, respectively, up to 4.5×10-3±0.0012 μmol/L and 911.1% compared with nature Cu, Zn-SOD.
Finally, its mechanism was also discussed.
In summary, this method about the simulation strategies will provide a novel idea for exploiting new-type biocompatible and highly reactive antioxidants.
American Psychological Association (APA)
Wang, Jianfeng& Li, Xiaoxiao& He, Yufeng& Song, Pengfei& Wang, Rongmin. 2018. Preparation of Keratin-Glycine Metal Complexes and Their Scavenging Activity for Superoxide Anion Radicals. International Journal of Polymer Science،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1175006
Modern Language Association (MLA)
Wang, Jianfeng…[et al.]. Preparation of Keratin-Glycine Metal Complexes and Their Scavenging Activity for Superoxide Anion Radicals. International Journal of Polymer Science No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1175006
American Medical Association (AMA)
Wang, Jianfeng& Li, Xiaoxiao& He, Yufeng& Song, Pengfei& Wang, Rongmin. Preparation of Keratin-Glycine Metal Complexes and Their Scavenging Activity for Superoxide Anion Radicals. International Journal of Polymer Science. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1175006
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1175006