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Characterization of Metabolically Healthy Obese People and Metabolically Unhealthy Normal-Weight People in a General Population Cohort of the ABCD Study
Joint Authors
Giordano, Carla
Buscemi, Silvio
Chiarello, Pierfilippo
Buscemi, Carola
Corleo, Davide
Massenti, Maria Fatima
Barile, Anna Maria
Rosafio, Giuseppe
Maniaci, Vincenza
Settipani, Valentina
Cosentino, Loretta
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-03
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
There is actually no consensus about the possibility that in some instances, obesity may be a benign metabolically healthy (MH) condition as opposed to a normal-weight but metabolically unhealthy (MUH) state.
The aim of this study was to characterize MH condition and to investigate possible associations with metabolic and cardiovascular complications.
One thousand nineteen people (range of age 18–90 years) of the cohort of the ABCD_2 study were investigated.
Participants were classified as normal weight (BMI < 24.9 kg/m2) or overweight-obese (BMI ≥25 kg/m2); they were also classified as MH in the presence of 0-1 among the following conditions: (a) prediabetes/type 2 diabetes, (b) hypertension, (c) hypertriglyceridemia or low HDL cholesterolemia, and (d) hypercholesterolemia.
MUH condition was diagnosed if ≥2 of the conditions listed were found.
The prevalence of overweight/obese people was 71.1%, of whom 27.4% were found to be MH.
In addition, 36.7% of the normal-weight participants were MUH.
HOMA-IR, high sensitivity C-reactive protein, and the carotid intima-media thickness were significantly different in the 4 subgroups (P<0.001), with higher values observed in the MUH normal-weight and obese groups.
In conclusion, this study highlights the importance of identifying a MH condition in normal-weight and in obese people in order to offer better treatment.
American Psychological Association (APA)
Buscemi, Silvio& Chiarello, Pierfilippo& Buscemi, Carola& Corleo, Davide& Massenti, Maria Fatima& Barile, Anna Maria…[et al.]. 2017. Characterization of Metabolically Healthy Obese People and Metabolically Unhealthy Normal-Weight People in a General Population Cohort of the ABCD Study. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1175017
Modern Language Association (MLA)
Buscemi, Silvio…[et al.]. Characterization of Metabolically Healthy Obese People and Metabolically Unhealthy Normal-Weight People in a General Population Cohort of the ABCD Study. Journal of Diabetes Research No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1175017
American Medical Association (AMA)
Buscemi, Silvio& Chiarello, Pierfilippo& Buscemi, Carola& Corleo, Davide& Massenti, Maria Fatima& Barile, Anna Maria…[et al.]. Characterization of Metabolically Healthy Obese People and Metabolically Unhealthy Normal-Weight People in a General Population Cohort of the ABCD Study. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1175017
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1175017