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Evaluation of the Morphology and Biocompatibility of Natural Silk FibersAgar Blend Scaffolds for Tissue Regeneration
Joint Authors
Hiep, Nguyen Thi
Niem, Vo Van Thanh
Hai, Nguyen Dai
Ngoc Tuan Anh, Mai
Huynh, Khon Chan
Thu-Hien, Luong
Thanh-Truc, Nguyen
Toi, Vo Van
Bao, Bui Chi
Chuong, Pham Dinh
Source
International Journal of Polymer Science
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-18
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
This study was aimed to develop a tissue engineering scaffold by incorporation of Bombyx mori silk fiber (BMSF) and agar.
This promised the improvement in enhancing their advantageous properties as well as limiting their defects without occurring chemical reactions or crosslink formation.
The morphology and chemical structure of scaffolds were observed using scanning electron microscope (SEM) observation and Fourier transform infrared (FT-IR) spectra.
The SEM results show that scaffolds containing BMSF have microporous structures, which are suitable for cell adhesion.
Agar scaffolds, by contrast, had much more flat morphology.
FT-IR spectra confirm that no modifications to BMSF happened in scaffolds, which indicates that there was no chemical reaction or crosslink formation between silk and agar in this process.
Furthermore, the biocompatibility of scaffolds was performed in the mouse’s subcutaneous part of the dorsal region for 15 days, followed by Haematoxylin and Eosin (H&E) staining.
H&E staining results demonstrate that scaffolds had good biocompatibility and there was no sign of the body rejection in all of samples.
The results from animal study show that SA scaffolds have the most stable structure for cell adhesion compared with those single materials.
American Psychological Association (APA)
Thu-Hien, Luong& Thanh-Truc, Nguyen& Toi, Vo Van& Huynh, Khon Chan& Bao, Bui Chi& Niem, Vo Van Thanh…[et al.]. 2018. Evaluation of the Morphology and Biocompatibility of Natural Silk FibersAgar Blend Scaffolds for Tissue Regeneration. International Journal of Polymer Science،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1175142
Modern Language Association (MLA)
Thu-Hien, Luong…[et al.]. Evaluation of the Morphology and Biocompatibility of Natural Silk FibersAgar Blend Scaffolds for Tissue Regeneration. International Journal of Polymer Science No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1175142
American Medical Association (AMA)
Thu-Hien, Luong& Thanh-Truc, Nguyen& Toi, Vo Van& Huynh, Khon Chan& Bao, Bui Chi& Niem, Vo Van Thanh…[et al.]. Evaluation of the Morphology and Biocompatibility of Natural Silk FibersAgar Blend Scaffolds for Tissue Regeneration. International Journal of Polymer Science. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1175142
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1175142