A Comparison Study of Antiultraviolet and Sustained Release Properties of PolydopamineAvermectin Microcapsule and Microsphere
Joint Authors
Shen, Zhichuan
Zhou, Xinhua
Qiu, Huina
Xu, Hua
Chen, Huayao
Zhou, Hongjun
Source
International Journal of Polymer Science
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-30
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
By using dopamine (DA) as the monomer, the model drug avermectin (AVM) was loaded on polydopamine microspheres (AVM/PDAMS) and polydopamine microcapsules (AVM@PDAMC) by the method of impregnation and encapsulation, respectively.
The materials’ structures were systematically characterized using Fourier transform infrared spectroscopy (FTIR), zeta potential analysis, scanning electron microscopy (SEM), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC).
The comparison of antiultraviolet capability as well as release behaviors under different pH values of the materials were studied.
The results showed that a spherical appearance was observed from both materials.
The use of AVM/PDAMS and AVM@PDAMC made the decomposition temperature of AVM increase to 235°C and 245°C, respectively.
After being exposed to ultraviolet light for 1400 min, the residual ratios of AVM of AVM/PDAMS and AVM@PDAMC were 42% and 54%, respectively.
Both AVM/PDAMS and AVM@PDAMC showed acid sensitivity.
AVM/PDAMS and AVM@PDAMC took about 13 h and 60 h to reach the release rate of 50% under pH 3.
The release process of AVM/PDAMS could be explained by the Weibull model at pH 3, while the release behavior of AVM@PDAMC fitted the Baker–Lonsdale equation.
At pH 7 and pH 9, both of the delivery materials followed the Korsmeyer–Peppas model and belonged to the Fick diffusion.
American Psychological Association (APA)
Shen, Zhichuan& Zhou, Xinhua& Qiu, Huina& Xu, Hua& Chen, Huayao& Zhou, Hongjun. 2018. A Comparison Study of Antiultraviolet and Sustained Release Properties of PolydopamineAvermectin Microcapsule and Microsphere. International Journal of Polymer Science،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1175279
Modern Language Association (MLA)
Shen, Zhichuan…[et al.]. A Comparison Study of Antiultraviolet and Sustained Release Properties of PolydopamineAvermectin Microcapsule and Microsphere. International Journal of Polymer Science No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1175279
American Medical Association (AMA)
Shen, Zhichuan& Zhou, Xinhua& Qiu, Huina& Xu, Hua& Chen, Huayao& Zhou, Hongjun. A Comparison Study of Antiultraviolet and Sustained Release Properties of PolydopamineAvermectin Microcapsule and Microsphere. International Journal of Polymer Science. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1175279
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1175279