Preparation and Application in Drug Storage and Delivery of Agarose Nanoparticles
Joint Authors
Ortega, Francisco
Rubio, Ramón G.
Guzman, Eduardo
Argudo, Pablo G.
Lucia, Alejandro
Source
International Journal of Polymer Science
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-19
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
In this work, monodisperse agarose gel nanoparticles were prepared using a W/O microemulsion as a template to control the size of the obtained particles.
The combination of this template method with a temperature-induced gelling and a solvent exchange methodology has allowed preparing stable aqueous dispersions of monodisperse agarose gel nanoparticles in water.
The average size, measured as an apparent hydrodynamic diameter, of the obtained particles was around 150 nm.
The ability of the obtained hydrogel particles for the encapsulation and release of a synthetic insecticide (azamethiphos) was tested.
The results evidence that the insecticide molecules encapsulated in the fabricated nanoparticles are released following a diffusion-controlled mechanism.
These results combined with the biodegradability of the agarose provide the bases for the design of a new vector with application in the control of parasites in water reservoirs.
American Psychological Association (APA)
Argudo, Pablo G.& Guzman, Eduardo& Lucia, Alejandro& Rubio, Ramón G.& Ortega, Francisco. 2018. Preparation and Application in Drug Storage and Delivery of Agarose Nanoparticles. International Journal of Polymer Science،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1175295
Modern Language Association (MLA)
Argudo, Pablo G.…[et al.]. Preparation and Application in Drug Storage and Delivery of Agarose Nanoparticles. International Journal of Polymer Science No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1175295
American Medical Association (AMA)
Argudo, Pablo G.& Guzman, Eduardo& Lucia, Alejandro& Rubio, Ramón G.& Ortega, Francisco. Preparation and Application in Drug Storage and Delivery of Agarose Nanoparticles. International Journal of Polymer Science. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1175295
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1175295