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Sentry Bioconvertible Inferior Vena Cava Filter: Study of Stages of Incorporation in an Experimental Ovine Model
Joint Authors
Gaines, Peter A.
Crowley, Gordon
Horan, Steven
MacDonagh, Megan
McLucas, Emily
Rosenthal, David
Strong, Ashley
Sweet, Michael
Panchal, Deepal K.
Kolodgie, Frank D.
Source
International Journal of Vascular Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The Sentry inferior vena cava (IVC) filter is designed to provide temporary protection from pulmonary embolism (PE) and then bioconvert to become incorporated in the vessel wall, leaving a patent IVC lumen.
Objective.
To evaluate the performance and stages of incorporation of the Sentry IVC filter in an ovine model.
Methods.
Twenty-four bioconvertible devices and 1 control retrievable filter were implanted in the infrarenal IVC of 25 sheep, with extensive daily monitoring and intensive imaging.
Vessels and devices were analyzed at early (≤98 days, n = 10) and late (180 ± 30 days, n = 14 study devices, 1 control) termination and necropsy time-points.
Results.
Deployment success was 100% with all devices confirmed in filtering configuration, there were no filter-related complications, and bioconversion was 100% at termination with vessels widely patent.
By 98 days for all early-incorporation analysis animals, the stabilizing cylindrical part of the Sentry frame was incorporated in the vessel wall, and the filter arms were retracted.
By 180 days for all late-incorporation analysis animals, the filter arms as well as frames were stably incorporated.
Conclusions.
Through 180 days, there were no filter-related complications, and the study devices were all bioconverted and stably incorporated, leaving all IVCs patent.
American Psychological Association (APA)
Gaines, Peter A.& Kolodgie, Frank D.& Crowley, Gordon& Horan, Steven& MacDonagh, Megan& McLucas, Emily…[et al.]. 2018. Sentry Bioconvertible Inferior Vena Cava Filter: Study of Stages of Incorporation in an Experimental Ovine Model. International Journal of Vascular Medicine،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1175788
Modern Language Association (MLA)
Gaines, Peter A.…[et al.]. Sentry Bioconvertible Inferior Vena Cava Filter: Study of Stages of Incorporation in an Experimental Ovine Model. International Journal of Vascular Medicine No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1175788
American Medical Association (AMA)
Gaines, Peter A.& Kolodgie, Frank D.& Crowley, Gordon& Horan, Steven& MacDonagh, Megan& McLucas, Emily…[et al.]. Sentry Bioconvertible Inferior Vena Cava Filter: Study of Stages of Incorporation in an Experimental Ovine Model. International Journal of Vascular Medicine. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1175788
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1175788