Tumour-Associated Macrophages (TAMs) in Colon Cancer and How to Reeducate Them
Joint Authors
Lila, M. A. M.
Nik Abd. Rahman, Nik Mohd Afizan
Yahaya, M. A. F.
Ismail, S.
Zainol, M.
Source
Journal of Immunology Research
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-25
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Tumour-associated macrophage (TAM) serves as the site in which most inflammatory cells coreside.
It plays an important role in determining the progression and metastasis of a tumour.
The characteristic of TAM is largely dependent on the stimuli present in its tumour microenvironment (TME).
Under this environment, however, M2 macrophages are found to be in abundance compared to M1 macrophages which later promote tumour progression.
Numerous studies have elucidated the relationship between TAM and the progression of tumour; hence, TAM has now been the subject of interest among researchers for anticancer therapy.
This review discusses the role of TAM in colorectal cancer (CRC) and some of the potential candidates that could reeducate TAM to fight against CRC.
It is with hope that this review will serve as the foundation in understanding TAM in CRC and helping other researchers to select the most suitable candidate to reeducate TAM that could assist in enhancing the tumouricidal activity of M1 macrophage and eventually repress the development of CRC.
American Psychological Association (APA)
Yahaya, M. A. F.& Lila, M. A. M.& Ismail, S.& Zainol, M.& Nik Abd. Rahman, Nik Mohd Afizan. 2019. Tumour-Associated Macrophages (TAMs) in Colon Cancer and How to Reeducate Them. Journal of Immunology Research،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1175847
Modern Language Association (MLA)
Yahaya, M. A. F.…[et al.]. Tumour-Associated Macrophages (TAMs) in Colon Cancer and How to Reeducate Them. Journal of Immunology Research No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1175847
American Medical Association (AMA)
Yahaya, M. A. F.& Lila, M. A. M.& Ismail, S.& Zainol, M.& Nik Abd. Rahman, Nik Mohd Afizan. Tumour-Associated Macrophages (TAMs) in Colon Cancer and How to Reeducate Them. Journal of Immunology Research. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1175847
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1175847