Nanomaterial Exposure Induced Neutrophil Extracellular Traps: A New Target in Inflammation and Innate Immunity
Joint Authors
Liu, Yi
Herrmann, Martin
Zhao, Yi
Yang, Hang
Marion, Tony N.
Zhang, Lingshu
Cao, Xue
Hu, Huifang
Source
Journal of Immunology Research
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Nanotechnology has become a novel subject with impact in many research and technology areas.
Nanoparticles (NPs), as a key component in nanotechnology, are widely used in many areas such as optical, magnetic, electrical, and mechanical engineering.
The biomedical and pharmaceutical industries have embraced NPs as a viable drug delivery modality.
As such, the potential for NP-induced cytotoxicity has emerged as a major concern for NP drug delivery systems.
Thus, it is important to understand how NPs affect the innate immune system.
As the most abundant myeloid cell type in innate immune responses, neutrophils are critical for concerns about potentially toxic side effects of NPs.
When activated by innate immune stimuli, neutrophils may initiate NETosis to release neutrophil extracellular traps (NETs).
Herein, we have reviewed the relationship between NPs and the induction of NETosis and release of NETs.
American Psychological Association (APA)
Yang, Hang& Marion, Tony N.& Liu, Yi& Zhang, Lingshu& Cao, Xue& Hu, Huifang…[et al.]. 2019. Nanomaterial Exposure Induced Neutrophil Extracellular Traps: A New Target in Inflammation and Innate Immunity. Journal of Immunology Research،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1176057
Modern Language Association (MLA)
Yang, Hang…[et al.]. Nanomaterial Exposure Induced Neutrophil Extracellular Traps: A New Target in Inflammation and Innate Immunity. Journal of Immunology Research No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1176057
American Medical Association (AMA)
Yang, Hang& Marion, Tony N.& Liu, Yi& Zhang, Lingshu& Cao, Xue& Hu, Huifang…[et al.]. Nanomaterial Exposure Induced Neutrophil Extracellular Traps: A New Target in Inflammation and Innate Immunity. Journal of Immunology Research. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1176057
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1176057