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Functions of Exosomes in the Triangular Relationship between the Tumor, Inflammation, and Immunity in the Tumor Microenvironment
Joint Authors
Nasser, M. I.
Zhao, Mingyi
Shen, Jie
He, Qingnan
Wang, Tiantian
Qu, Shujuan
Source
Journal of Immunology Research
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-08-01
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Exosomes are extracellular vesicles that contain diverse components such as genetic materials, proteins, and lipids.
Owing to their distinct derivation and tissue specificity, exosomes act as double-edged swords during the development of neoplasms.
On the one hand, tumor-derived exosomes can modulate the immune system during tumorigenesis by regulating inflammatory cell infiltration and oxidative stress and by promoting epithelial-to-mesenchymal transition and immune-induced tumor dormancy.
On the other hand, components of specific immune cell-derived exosomes may contribute to the efficacy of antitumor immunotherapy.
In this review, we demonstrate the pivotal role of exosomes in the triangular relationship in the tumor microenvironment between the tumor, inflammation, and immunity, which may provide potential strategies for tumor immunotherapy at genetic and cellular levels.
American Psychological Association (APA)
Wang, Tiantian& Nasser, M. I.& Shen, Jie& Qu, Shujuan& He, Qingnan& Zhao, Mingyi. 2019. Functions of Exosomes in the Triangular Relationship between the Tumor, Inflammation, and Immunity in the Tumor Microenvironment. Journal of Immunology Research،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1176176
Modern Language Association (MLA)
Wang, Tiantian…[et al.]. Functions of Exosomes in the Triangular Relationship between the Tumor, Inflammation, and Immunity in the Tumor Microenvironment. Journal of Immunology Research No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1176176
American Medical Association (AMA)
Wang, Tiantian& Nasser, M. I.& Shen, Jie& Qu, Shujuan& He, Qingnan& Zhao, Mingyi. Functions of Exosomes in the Triangular Relationship between the Tumor, Inflammation, and Immunity in the Tumor Microenvironment. Journal of Immunology Research. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1176176
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1176176