Efficiency of Multiparticulate Delivery Systems Loaded with Flufenamic Acid Designed for Burn Wound Healing Applications
Joint Authors
Albu, Mădălina
Marin, Stefania
Marin, Minodora Maria
Danila, Elena
Ghica, Mihaela Violeta
Ignat, Simona Rebeca
Lazar, Andreea Daniela
Udeanu, Denisa Ioana
Dinescu, Sorina
Marieta, Costache
Source
Journal of Immunology Research
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-05
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Burns are soft tissue injuries that require particular care for wound healing.
Current tissue engineering approaches are aimed at identifying the most efficient treatment combinations to restore the tissue properties and function by using adapted scaffolds or delivery platforms for tissue repair and regeneration by triggering molecules.
To reduce the inflammation associated with skin burns, the addition of an anti-inflammatory factor in these scaffolds would greatly increase the quality of the therapy.
Therefore, this study is aimed at obtaining and validating a novel multiparticulate system based on a collagen matrix with controlled delivery of flufenamic acid anti-inflammatory drug for burn wound healing applications.
In this work, we have characterized the properties and biocompatibility of these multiparticulate drug delivery systems (MDDS) and we have demonstrated their efficiency against burns and soft tissue lesions, particularly when the drug was microencapsulated, and thus with a controlled release.
This study contributes to the advancement in therapy of burns and burn wound healing applications.
American Psychological Association (APA)
Dinescu, Sorina& Ignat, Simona Rebeca& Lazar, Andreea Daniela& Marin, Stefania& Danila, Elena& Marin, Minodora Maria…[et al.]. 2019. Efficiency of Multiparticulate Delivery Systems Loaded with Flufenamic Acid Designed for Burn Wound Healing Applications. Journal of Immunology Research،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1176217
Modern Language Association (MLA)
Dinescu, Sorina…[et al.]. Efficiency of Multiparticulate Delivery Systems Loaded with Flufenamic Acid Designed for Burn Wound Healing Applications. Journal of Immunology Research No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1176217
American Medical Association (AMA)
Dinescu, Sorina& Ignat, Simona Rebeca& Lazar, Andreea Daniela& Marin, Stefania& Danila, Elena& Marin, Minodora Maria…[et al.]. Efficiency of Multiparticulate Delivery Systems Loaded with Flufenamic Acid Designed for Burn Wound Healing Applications. Journal of Immunology Research. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1176217
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1176217