The effect of some plant oils on liver efficiency after exposure to cement in rats

Abstract EN

This study aimed at investigating possible protective effects of some plant oils on cement induced liver toxicity in rats.

Methods: Forty Sprague Dawley rats divided into five groups (8 rats/group; four males and four females).

Animals fed for 4 weeks the following diets: (I) basal/standard diet, negative control; (II) basal diet contains cement (1.5g/Kg body weight), positive control; (III, IV, and V) basal diet contains 10% (coconut oil or flaxseed oil or olive oil) plus the same dose of cement, as treatment groups.

Results: Cement exposure resulted in a significant elevation in liver enzymes (Alanine transaminase (ALT), Aspartate transaminase (AST), lactate dehydrogenase (LDH), and along with elevating the level of hepatic tissue malondialdehyde (MDA).

Plant oils reinstated most of the altered measured parameters.

Conclusion: Supplementation of diet with coconut oil, flaxseed oil, and olive oil was effective in modulating some aspects of cement induced liver toxicity.