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Lower Urinary Tract Symptoms in Subjects with Subclinical Cerebral White Matter Lesions
Joint Authors
Mok, V. C. T.
Yee, Chi-Hang
Leung, Ching
Wong, Yuki Yu-Ting
Lee, Sylvia
Li, Jenny
Kwan, Pauline
Chu, Winnie Chiu-Wing
Ng, A. C. F.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-30
Country of Publication
Egypt
No. of Pages
5
Abstract EN
Aim.
We assessed the impact of cerebral white matter lesions (WMLs) on lower urinary tract symptoms in subjects with normal neurological and cognitive function.
Methods.
A cohort of community-dwelling subjects aged ≥65 years were recruited to undergo MRI brain assessment.
WMLs were graded using the Fazekas scale from 0 to 3.
A separate telephone interview was carried out to assess the urinary symptoms in these subjects using the questionnaire Overactive Bladder-Validated 8-Question Awareness Tool (OAB-V8).
Results.
800 community-dwelling elderly subjects were recruited to undergo MRI brain.
In this cohort, 431 subjects responded to the telephone interview concerning their urinary symptoms.
Among the respondents, 21.1% did not exhibit any WML on their MRI brain.
Most of the subjects (52.6%) exhibited grade 1 WML.
On logistic regression, age was found to be positively correlated with the Fazekas score (correlation coefficient 0.203, p≤0.01).
Using a cutoff of 8 on OAB-V8, 22% of the respondents experienced OAB.
Presence of WML, hypertension, or diabetes mellitus was not found to be correlated with storage urinary symptoms or OAB-V8 total score.
Multiple logistic regression analysis did not show the presence of WML to be associated with the diagnosis of OAB (adjusted OR 1.13, 95% CI 0.65–1.96, p=0.659).
Conclusions.
WML is associated with age and is common in the elderly population.
Mild WML is subclinical, with no obvious neurological and urinary symptoms.
Our cohort did not demonstrate a relationship between WML and lower urinary tract symptoms.
American Psychological Association (APA)
Yee, Chi-Hang& Leung, Ching& Wong, Yuki Yu-Ting& Lee, Sylvia& Li, Jenny& Kwan, Pauline…[et al.]. 2018. Lower Urinary Tract Symptoms in Subjects with Subclinical Cerebral White Matter Lesions. Journal of Aging Research،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1180731
Modern Language Association (MLA)
Yee, Chi-Hang…[et al.]. Lower Urinary Tract Symptoms in Subjects with Subclinical Cerebral White Matter Lesions. Journal of Aging Research No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1180731
American Medical Association (AMA)
Yee, Chi-Hang& Leung, Ching& Wong, Yuki Yu-Ting& Lee, Sylvia& Li, Jenny& Kwan, Pauline…[et al.]. Lower Urinary Tract Symptoms in Subjects with Subclinical Cerebral White Matter Lesions. Journal of Aging Research. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1180731
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1180731