Contribution of Zinc and Zinc Transporters in the Pathogenesis of Inflammatory Bowel Diseases
Joint Authors
Fukada, Toshiyuki
Ohashi, Wakana
Source
Journal of Immunology Research
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-10
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Intestinal epithelial cells cover the surface of the intestinal tract.
The cells are important for preserving the integrity of the mucosal barriers to protect the host from luminal antigens and pathogens.
The mucosal barriers are maintained by the continuous and rapid self-renewal of intestinal epithelial cells.
Defects in the self-renewal of these cells are associated with gastrointestinal diseases, including inflammatory bowel diseases and diarrhea.
Zinc is an essential trace element for living organisms, and zinc deficiency is closely linked to the impaired mucosal integrity.
Recent evidence has shown that zinc transporters contribute to the barrier function of intestinal epithelial cells.
In this review, we describe the recent advances in understanding the role of zinc and zinc transporters in the barrier function and homeostasis of intestinal epithelial cells.
American Psychological Association (APA)
Ohashi, Wakana& Fukada, Toshiyuki. 2019. Contribution of Zinc and Zinc Transporters in the Pathogenesis of Inflammatory Bowel Diseases. Journal of Immunology Research،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1180948
Modern Language Association (MLA)
Ohashi, Wakana& Fukada, Toshiyuki. Contribution of Zinc and Zinc Transporters in the Pathogenesis of Inflammatory Bowel Diseases. Journal of Immunology Research No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1180948
American Medical Association (AMA)
Ohashi, Wakana& Fukada, Toshiyuki. Contribution of Zinc and Zinc Transporters in the Pathogenesis of Inflammatory Bowel Diseases. Journal of Immunology Research. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1180948
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1180948