Autoimmune Hepatitis—Immunologically Triggered Liver Pathogenesis—Diagnostic and Therapeutic Strategies
Joint Authors
Brandacher, Gerald
Sucher, Robert
Sucher, Elisabeth
Gradistanac, Tanja
Berg, Thomas
Schneeberger, Stefan
Source
Journal of Immunology Research
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-25
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Abstract EN
Autoimmune hepatitis (AIH) is a severe liver disease that arises in genetically predisposed male and female individuals worldwide.
Diagnosis of AIH is made clinically applying diagnostic scores; however, the heterotopic disease phenotype often makes a rapid determination of disease challenging.
AIH responds favorably to steroids and pharmacologic immunosuppression, and liver transplantation is only necessary in cases with acute liver failure or end-stage liver cirrhosis.
Recurrence or development of de novo AIH after transplantation is possible, and treatment is similar to standard AIH therapy.
Current experimental investigations of T cell-mediated autoimmune pathways and analysis of changes within the intestinal microbiome might advance our knowledge on the pathogenesis of AIH and trigger a spark of hope for novel therapeutic strategies.
American Psychological Association (APA)
Sucher, Elisabeth& Sucher, Robert& Gradistanac, Tanja& Brandacher, Gerald& Schneeberger, Stefan& Berg, Thomas. 2019. Autoimmune Hepatitis—Immunologically Triggered Liver Pathogenesis—Diagnostic and Therapeutic Strategies. Journal of Immunology Research،Vol. 2019, no. 2019, pp.1-19.
https://search.emarefa.net/detail/BIM-1181078
Modern Language Association (MLA)
Sucher, Elisabeth…[et al.]. Autoimmune Hepatitis—Immunologically Triggered Liver Pathogenesis—Diagnostic and Therapeutic Strategies. Journal of Immunology Research No. 2019 (2019), pp.1-19.
https://search.emarefa.net/detail/BIM-1181078
American Medical Association (AMA)
Sucher, Elisabeth& Sucher, Robert& Gradistanac, Tanja& Brandacher, Gerald& Schneeberger, Stefan& Berg, Thomas. Autoimmune Hepatitis—Immunologically Triggered Liver Pathogenesis—Diagnostic and Therapeutic Strategies. Journal of Immunology Research. 2019. Vol. 2019, no. 2019, pp.1-19.
https://search.emarefa.net/detail/BIM-1181078
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1181078