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Treatment of In-Stent Restenosis by Excimer Laser Coronary Atherectomy and Drug-Coated Balloon: Serial Assessment with Optical Coherence Tomography
Joint Authors
Ashikaga, Takashi
Miyazaki, Toru
Kurihara, Ken
Hirao, Kenzo
Fukushima, Taku
Hatano, Yu
Sasaoka, Taro
Ono, Yuichi
Shimizu, Shigeo
Otomo, Kenichiro
Source
Journal of Interventional Cardiology
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objectives.
We aimed to compare the results of neointimal modification before drug-coated balloon (DCB) treatment with excimer laser coronary atherectomy (ELCA) plus scoring balloon predilation versus scoring balloon alone in patients presenting with in-stent restenosis (ISR).
Background.
Treatment of ISR with ELCA typically results in superior acute gain by neointima debulking.
However, the efficacy of combination therapy of ELCA and DCB remains unknown.
Methods.
A total of 42 patients (44 ISR lesions) undergoing DCB treatment with ELCA plus scoring balloon (ELCA group, n = 18) or scoring balloon alone (non-ELCA group, n = 24) were evaluated via serial assessment by optical coherence tomography (OCT) performed before, after intervention, and at 6 months.
Results.
Although there was significantly greater frequency of diffuse restenosis and percent diameter stenosis (%DS) after intervention in the ELCA group, comparable result was shown in %DS, late lumen loss, and binary angiographic restenosis at follow-up.
On OCT analysis, a decreased tendency in the minimum lumen area and a significant decrease in the minimum stent area were observed in the ELCA group between 6-month follow-up and after intervention (-0.89 ± 1.36 mm2 vs.
-0.09 ± 1.25 mm2, p = 0.05, -0.49 ± 1.48 mm2 vs.
0.28 ± 0.78 mm2, p = 0.03, respectively).
The changes in the neointimal area were similar between the groups, and target lesion revascularization showed comparable rates at 1 year (11.1% vs.
11.4%, p = 0.85).
Conclusions.
Despite greater %DS after intervention, ELCA before DCB had possible benefit for late angiographic and clinical outcome.
American Psychological Association (APA)
Miyazaki, Toru& Ashikaga, Takashi& Fukushima, Taku& Hatano, Yu& Sasaoka, Taro& Kurihara, Ken…[et al.]. 2019. Treatment of In-Stent Restenosis by Excimer Laser Coronary Atherectomy and Drug-Coated Balloon: Serial Assessment with Optical Coherence Tomography. Journal of Interventional Cardiology،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1181249
Modern Language Association (MLA)
Miyazaki, Toru…[et al.]. Treatment of In-Stent Restenosis by Excimer Laser Coronary Atherectomy and Drug-Coated Balloon: Serial Assessment with Optical Coherence Tomography. Journal of Interventional Cardiology No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1181249
American Medical Association (AMA)
Miyazaki, Toru& Ashikaga, Takashi& Fukushima, Taku& Hatano, Yu& Sasaoka, Taro& Kurihara, Ken…[et al.]. Treatment of In-Stent Restenosis by Excimer Laser Coronary Atherectomy and Drug-Coated Balloon: Serial Assessment with Optical Coherence Tomography. Journal of Interventional Cardiology. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1181249
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1181249