Shock Index on Admission Is Associated with Coronary SlowNo Reflow in Patients with Acute Myocardial Infarction Undergoing Emergent Percutaneous Coronary Intervention
Joint Authors
Zheng, Jianlei
Wang, Qingcheng
Shen, Huimin
Mao, Huijuan
Yu, Fenghua
Wang, Haiqing
Source
Journal of Interventional Cardiology
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-07-25
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
Coronary slow/no reflow is not rare after successfully undergoing primary percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI), and shock index (SI) is an important factor for adverse cardiovascular prognosis.
In this study, we are to explore whether SI is associated with coronary slow/no reflow in patients with AMI following primary PCI.
Methods.
A total of 153 consecutive AMI patients undergoing primary PCI within 24 hours of symptom onset were included in this study.
The participants were divided into normal flow group (n=124) and slow/no reflow group (n=29) according to cineangiograms recorded during the period of PCI.
Cardiovascular risk factors, hematologic parameters, preoperative management of antithrombotic therapy, and baseline angiography were collected.
Results.
SI, plasma glucose, white blood cells (WBC) and neutrophil count, neutrophil to lymphocyte ratio (PLR), high sensitivity C-reactive protein (hs-CRP), probrain natriuretic peptide (pro-BNP), and Killip classification on admission and thrombus burden on initial angiography were significantly different between patients with and without slow/no reflow.
Multivariate analysis revealed that SI≥0.66, thrombus burden, and plasma glucose on admission were independent predictors for coronary slow/no reflow.
Preoperative management of tirofiban therapy improves initial thrombolysis in myocardial infarction (TIMI).
However, it has no effect on prognosis of slow/no reflow.
Conclusion.
Our findings demonstrated that slow/no reflow in patients with AMI following primary PCI was more likely associated with SI≥0.66, thrombus burden, and plasma glucose on admission.
SI as a predictor for coronary slow/no reflow should be further confirmed in the following more large-scale and prospective studies.
The clinical registration number is ChiCTR1900024447.
American Psychological Association (APA)
Wang, Qingcheng& Shen, Huimin& Mao, Huijuan& Yu, Fenghua& Wang, Haiqing& Zheng, Jianlei. 2019. Shock Index on Admission Is Associated with Coronary SlowNo Reflow in Patients with Acute Myocardial Infarction Undergoing Emergent Percutaneous Coronary Intervention. Journal of Interventional Cardiology،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1181277
Modern Language Association (MLA)
Wang, Qingcheng…[et al.]. Shock Index on Admission Is Associated with Coronary SlowNo Reflow in Patients with Acute Myocardial Infarction Undergoing Emergent Percutaneous Coronary Intervention. Journal of Interventional Cardiology No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1181277
American Medical Association (AMA)
Wang, Qingcheng& Shen, Huimin& Mao, Huijuan& Yu, Fenghua& Wang, Haiqing& Zheng, Jianlei. Shock Index on Admission Is Associated with Coronary SlowNo Reflow in Patients with Acute Myocardial Infarction Undergoing Emergent Percutaneous Coronary Intervention. Journal of Interventional Cardiology. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1181277
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1181277