Ultrasound-Assisted Enzymatic Extraction of Adenosine from Vietnamese Cordyceps militaris and Bioactivity Analysis of the Extract
Joint Authors
Ha, Huynh Ky Phuong
Vuong Hoai, Thanh
Nguyen Cao, Phuc
Phan Le Thao, My
Do, Tran Dat
Hoang Minh, Nam
Mai Thanh, Phong
Nguyen Huu, Hieu
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-05-26
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Vietnamese Cordyceps militaris (C.
militaris) has long been recognized as one of the most valuable traditional Chinese medicines.
In this study, adenosine was extracted from Vietnamese C.
militaris by ultrasound-assisted enzymatic extraction method (UAEE) using water as a solvent.
Then, the effects of five single factors on adenosine content including pH, enzyme-to-material ratio, ultrasonic power, ultrasonic time, and ultrasonic temperature were determined.
After that, three factors consisting of ultrasonic power, ultrasonic time, and ultrasonic temperature were chosen based on their effects on adenosine content.
The simultaneous influence of these factors on the adenosine content was investigated by response surface method using central composite design.
The adenosine content was evaluated by high-performance liquid chromatography method.
Under the optimal conditions, the extract was evaluated for antioxidant and anticancer bioactivities.
In addition, different extraction methods including aqueous extraction (AE), ultrasound-assisted extraction (UAE), and enzyme-assisted extraction (EAE) methods were carried out to compare with UAEE.
As a result, it can be concluded that UAEE is a promising method for adenosine extraction and further studies regarding isolation and purification need to be conducted.
American Psychological Association (APA)
Vuong Hoai, Thanh& Nguyen Cao, Phuc& Phan Le Thao, My& Do, Tran Dat& Hoang Minh, Nam& Ha, Huynh Ky Phuong…[et al.]. 2020. Ultrasound-Assisted Enzymatic Extraction of Adenosine from Vietnamese Cordyceps militaris and Bioactivity Analysis of the Extract. Journal of Chemistry،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1181371
Modern Language Association (MLA)
Vuong Hoai, Thanh…[et al.]. Ultrasound-Assisted Enzymatic Extraction of Adenosine from Vietnamese Cordyceps militaris and Bioactivity Analysis of the Extract. Journal of Chemistry No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1181371
American Medical Association (AMA)
Vuong Hoai, Thanh& Nguyen Cao, Phuc& Phan Le Thao, My& Do, Tran Dat& Hoang Minh, Nam& Ha, Huynh Ky Phuong…[et al.]. Ultrasound-Assisted Enzymatic Extraction of Adenosine from Vietnamese Cordyceps militaris and Bioactivity Analysis of the Extract. Journal of Chemistry. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1181371
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1181371