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Neutrophil Extracellular Traps and Microcrystals
Author
Source
Journal of Immunology Research
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Neutrophil extracellular traps represent a fascinating mechanism by which PMNs entrap extracellular microbes.
The primary purpose of this innate immune mechanism is thought to localize the infection at an early stage.
Interestingly, the ability of different microcrystals to induce NET formation has been recently described.
Microcrystals are insoluble crystals with a size of 1–100 micrometers that have different composition and shape.
Microcrystals have it in common that they irritate phagocytes including PMNs and typically trigger an inflammatory response.
This review is the first to summarize observations with regard to PMN activation and NET release induced by microcrystals.
Gout-causing monosodium urate crystals, pseudogout-causing calcium pyrophosphate dehydrate crystals, cholesterol crystals associated with atherosclerosis, silicosis-causing silica crystals, and adjuvant alum crystals are discussed.
American Psychological Association (APA)
Rada, Balázs. 2017. Neutrophil Extracellular Traps and Microcrystals. Journal of Immunology Research،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1181655
Modern Language Association (MLA)
Rada, Balázs. Neutrophil Extracellular Traps and Microcrystals. Journal of Immunology Research No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1181655
American Medical Association (AMA)
Rada, Balázs. Neutrophil Extracellular Traps and Microcrystals. Journal of Immunology Research. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1181655
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1181655