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The Role of Humoral Alloreactivity in Liver Transplantation: Lessons Learned and New Perspectives
Author
Source
Journal of Immunology Research
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-09
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
More than ten years after the initial description of the humoral theory of transplantation by Dr.
Paul I.
Terasaki, the significance of humoral alloimmunity in liver transplantation has yet to be clearly defined.
The liver allograft has an inherent tolerogenic capacity which confers its resistance to cell-mediated as well as antibody-mediated rejection.
Nevertheless, the protection against alloimmunity is not complete, and antibody-mediated tissue injury can occur in the liver graft under specific circumstances.
In this article the evidence on the clinicopathologic effects of donor-specific alloantibodies in liver transplantation will be examined and interpreted in parallel with lessons learned from renal transplantation.
The unique anatomic and immunologic features of the liver will be reviewed to gain new insights into the complex interactions between humoral immune system and the liver allograft.
American Psychological Association (APA)
Cheng, Elaine Y.. 2017. The Role of Humoral Alloreactivity in Liver Transplantation: Lessons Learned and New Perspectives. Journal of Immunology Research،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1181696
Modern Language Association (MLA)
Cheng, Elaine Y.. The Role of Humoral Alloreactivity in Liver Transplantation: Lessons Learned and New Perspectives. Journal of Immunology Research No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1181696
American Medical Association (AMA)
Cheng, Elaine Y.. The Role of Humoral Alloreactivity in Liver Transplantation: Lessons Learned and New Perspectives. Journal of Immunology Research. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1181696
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1181696