Synthesis, Characterization, Cyclic Voltammetry, and Biological Studies of Co(II), Ni(II), and Cu(II) Complexes of a Tridentate Schiff Base, 1-((E)-(2-Mercaptophenylimino) Methyl) Naphthalen-2-ol (H2L1)
Joint Authors
Kuate, Maurice
Conde, Mariam Asseng
Ngandung Mainsah, Evans
Paboudam, Awawou G.
Tchieno, Francis Merlin M.
Ketchemen, Kevin I. Y.
Tonle Kenfack, Ignas
Ndifon, Peter T.
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-21, 21 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-09
Country of Publication
Egypt
No. of Pages
21
Main Subjects
Abstract EN
A novel tridentate Schiff base, 1-((E)-(2-mercaptophenylimino) methyl) naphthalen-2-ol (H2L1), was synthesized by the condensation reaction of 2-hydroxy-1-naphthaldehyde with 2-aminothiophenol in absolute ethanol.
The resulting ligand was reacted with Co(II), Ni(II), and Cu(II) ions to obtain tetrahedral CoL1, NiL1, and square planar CuL1 complexes.
The Schiff base and its metal complexes were characterized using 1H-NMR, microanalysis, FT-IR, UV-visible, and mass spectroscopy (ESI-MS).
All the compounds are soluble in DMSO and DMF.
Spectroscopic studies show that the ligand coordinates to the metal center through the azomethine nitrogen, naphthoxide oxygen, and thiophenoxide sulfur to form a tridentate chelate system.
Conductance measurements show that these compounds are molecular in solution.
Cyclic voltammetry studies show Co(III)/Co(II) and Cu(II)/Cu(I) redox systems to be quasi-reversible involving a monoelectronic transfer while Ni(III)/Ni(II) was irreversible.
In vitro antibacterial and antifungal activity against five bacterial strains (Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Enterococcus faecalis, and Proteus mirabilis) and five fungal strains (Candida albicans, Candida glabrata, Candida tropicalis, Candida krusei, and Candida parapsilosis) showed no antifungal activity but moderate antibacterial activity on E.
coli, S.
aureus, P.
aeruginosa, and P.
mirabilis bacterial strains.
Antioxidant studies reveal that the ligand and its Cu(II) complex are more potent than Co(II) and Ni(II) complexes to eliminate free radicals.
American Psychological Association (APA)
Kuate, Maurice& Conde, Mariam Asseng& Ngandung Mainsah, Evans& Paboudam, Awawou G.& Tchieno, Francis Merlin M.& Ketchemen, Kevin I. Y.…[et al.]. 2020. Synthesis, Characterization, Cyclic Voltammetry, and Biological Studies of Co(II), Ni(II), and Cu(II) Complexes of a Tridentate Schiff Base, 1-((E)-(2-Mercaptophenylimino) Methyl) Naphthalen-2-ol (H2L1). Journal of Chemistry،Vol. 2020, no. 2020, pp.1-21.
https://search.emarefa.net/detail/BIM-1181851
Modern Language Association (MLA)
Kuate, Maurice…[et al.]. Synthesis, Characterization, Cyclic Voltammetry, and Biological Studies of Co(II), Ni(II), and Cu(II) Complexes of a Tridentate Schiff Base, 1-((E)-(2-Mercaptophenylimino) Methyl) Naphthalen-2-ol (H2L1). Journal of Chemistry No. 2020 (2020), pp.1-21.
https://search.emarefa.net/detail/BIM-1181851
American Medical Association (AMA)
Kuate, Maurice& Conde, Mariam Asseng& Ngandung Mainsah, Evans& Paboudam, Awawou G.& Tchieno, Francis Merlin M.& Ketchemen, Kevin I. Y.…[et al.]. Synthesis, Characterization, Cyclic Voltammetry, and Biological Studies of Co(II), Ni(II), and Cu(II) Complexes of a Tridentate Schiff Base, 1-((E)-(2-Mercaptophenylimino) Methyl) Naphthalen-2-ol (H2L1). Journal of Chemistry. 2020. Vol. 2020, no. 2020, pp.1-21.
https://search.emarefa.net/detail/BIM-1181851
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1181851