Synthesis and Performance of Hybrid Hydrogels Loaded with Methylene Blue and Its Use for Antimicrobial Photodynamic Inactivation
Joint Authors
Nadtoka, Oksana
Virych, Pavlo
Nadtoka, Serhiy
Kutsevol, Nataliya
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-23
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Development and characterization of hybrid hydrogels loaded with methylene blue, which are designed to apply for photodynamic therapy, are presented.
Hybrid hydrogels were synthesized by grafting polyacrylamide onto dextran/dextran sulfate sodium salt using N, N′-methylene-bis-acrylamide as a cross-linker.
The differences in microstructure of synthesized hydrogels were proved by scanning electron microscopy.
FTIR spectra testify that the chemical nature of hydrogel components affects the hydrogel hydrophilicity.
The swelling properties of hydrogels in water and absorption/desorption hydrogels’ ability towards methylene blue were studied.
It was shown that dye sorption was dependent on the hydrogel type.
The hydrogel based on dextran and polyacrylamide revealed the highest ability to release absorbed dye.
The bactericidal effect of this hydrogel loaded with methylene blue and activated by red light in suspension and solid medium of S.
aureus was tested.
The increase of bactericidal activity of hybrid hydrogel was dependent on radiation doses.
American Psychological Association (APA)
Nadtoka, Oksana& Virych, Pavlo& Nadtoka, Serhiy& Kutsevol, Nataliya. 2020. Synthesis and Performance of Hybrid Hydrogels Loaded with Methylene Blue and Its Use for Antimicrobial Photodynamic Inactivation. Journal of Chemistry،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1182070
Modern Language Association (MLA)
Nadtoka, Oksana…[et al.]. Synthesis and Performance of Hybrid Hydrogels Loaded with Methylene Blue and Its Use for Antimicrobial Photodynamic Inactivation. Journal of Chemistry No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1182070
American Medical Association (AMA)
Nadtoka, Oksana& Virych, Pavlo& Nadtoka, Serhiy& Kutsevol, Nataliya. Synthesis and Performance of Hybrid Hydrogels Loaded with Methylene Blue and Its Use for Antimicrobial Photodynamic Inactivation. Journal of Chemistry. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1182070
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1182070