Macrophage Polarization in Cerebral Aneurysm: Perspectives and Potential Targets
Joint Authors
Jian, Zhihong
Xiong, Xiaoxing
Shao, Lingmin
Qin, Xingping
Liu, Jia
Liu, Renzhong
Source
Journal of Immunology Research
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Cerebral aneurysms (CAs) have become a health burden not only because their rupture is life threatening, but for a series of devastating complications left in survivors.
It is well accepted that sustained chronic inflammation plays a crucial role in the pathology of cerebral aneurysms.
In particular, macrophages have been identified as critical effector cells orchestrating inflammation in CAs.
In recent years, dysregulated M1/M2 polarization has been proposed to participate in the progression of CAs.
Although the pathological mechanisms of M1/M2 imbalance in CAs remain largely unknown, recent advances have been made in the understanding of the molecular basis and other immune cells involving in this sophisticated network.
We provide a concise overview of the mechanisms associated with macrophage plasticity and the emerging molecular targets.
American Psychological Association (APA)
Shao, Lingmin& Qin, Xingping& Liu, Jia& Jian, Zhihong& Xiong, Xiaoxing& Liu, Renzhong. 2017. Macrophage Polarization in Cerebral Aneurysm: Perspectives and Potential Targets. Journal of Immunology Research،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1182118
Modern Language Association (MLA)
Shao, Lingmin…[et al.]. Macrophage Polarization in Cerebral Aneurysm: Perspectives and Potential Targets. Journal of Immunology Research No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1182118
American Medical Association (AMA)
Shao, Lingmin& Qin, Xingping& Liu, Jia& Jian, Zhihong& Xiong, Xiaoxing& Liu, Renzhong. Macrophage Polarization in Cerebral Aneurysm: Perspectives and Potential Targets. Journal of Immunology Research. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1182118
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1182118