Physicochemical Characterization and Biocompatibility of SPION@Plasmonic @Chitosan Core-Shell Nanocomposite Biosynthesized from Fungus Species
Joint Authors
El-Hallouty, Salwa M.
Eid, M. M.
El-Manawaty, M.
Abdelzaher, F. H.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-05
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
In this work we aim to manipulate green route for the synthesis of core-shell maghemite-based Ag nanoparticles functionalized with chitosan.
Three fungal species, Aspergillus deflectus, Fusarium oxysporum, and Penicillium pinophilum, were used in the process of synthesis to select the best among them for the production.
The physicochemical parameters of produced nanoparticles and mediated cytotoxicity assessment for their potential medical application have been performed using Fourier transform infrared (FTIR), UV/visible, vibrating sample magnetometer (VSM), dynamic light scattering (DLS), high-resolution transmission electron microscope (HRTEM), EDAX, and MTT to plot a cytotoxicity assessment report.
The results confirmed the formation of monodispersed γFe2O3@Ag@chitosan with low cytotoxicity against prostate (PC3), liver (HepG2), column (HCT116), and breast cancer (MCF7) ATCC cell lines.
In conclusion, these results prove the success of the green route used for the biosynthesis of γFe2O3@Ag@chitosan with parameters necessary for bioimaging, drug and gene delivery, and biosensing.
American Psychological Association (APA)
Eid, M. M.& El-Hallouty, Salwa M.& El-Manawaty, M.& Abdelzaher, F. H.. 2019. Physicochemical Characterization and Biocompatibility of SPION@Plasmonic @Chitosan Core-Shell Nanocomposite Biosynthesized from Fungus Species. Journal of Nanomaterials،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1182168
Modern Language Association (MLA)
Eid, M. M.…[et al.]. Physicochemical Characterization and Biocompatibility of SPION@Plasmonic @Chitosan Core-Shell Nanocomposite Biosynthesized from Fungus Species. Journal of Nanomaterials No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1182168
American Medical Association (AMA)
Eid, M. M.& El-Hallouty, Salwa M.& El-Manawaty, M.& Abdelzaher, F. H.. Physicochemical Characterization and Biocompatibility of SPION@Plasmonic @Chitosan Core-Shell Nanocomposite Biosynthesized from Fungus Species. Journal of Nanomaterials. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1182168
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1182168